Area of research
Hematology · Ophthalmology
Research interest
Research interests include Multiple Myeloma Research and Treatments, Ocular Oncology and Treatments, Protein Degradation and Inhibitors, and Cancer Genomics and Diagnostics.
Biallelic antigen escape is a mechanism of resistance to anti-CD38 antibodies in multiple myeloma
Genomics Define Malignant Transformation in Myeloma Precursor Conditions
Timing Genomic Antigen Loss in Multiple Myeloma Treated with T Cell–Redirecting Immunotherapies
Mutagenic Impact and Evolutionary Influence of Chemoradiotherapy in Hematologic Malignancies
Early genetic evolution of driver mutations in uveal melanoma
Genomic Classification and Individualized Prognosis in Multiple Myeloma
Impact of soluble BCMA and non–T-cell factors on refractoriness to BCMA-targeting T-cell engagers in multiple myeloma
Genomic Profiling to Contextualize the Results of Intervention for Smoldering Multiple Myeloma
Genomic Determinants of Resistance to Anti-BCMA Chimeric Antigen Receptor T-Cell (CART) Therapies in Patients with Relapsed/Refractory Multiple Myeloma
CD38 biallelic loss is a recurrent mechanism of resistance to anti-CD38 antibodies in multiple myeloma
Mechanisms of antigen escape from BCMA- or GPRC5D-targeted immunotherapies in multiple myeloma
PRAME induces genomic instability in uveal melanoma
The Impact of Soluble BCMA and BCMA Gain on Anti-BCMA Immunotherapies in Multiple Myeloma
RB1 loss triggers dependence on ESRRG in retinoblastoma
HDAC11 activity contributes to MEK inhibitor escape in uveal melanoma
Uphyloplot2: visualizing phylogenetic trees from single-cell RNA-seq data
Multiregional genetic evolution of metastatic uveal melanoma
Single-cell analysis reveals new evolutionary complexity in uveal melanoma
Single-cell analysis of olfactory neurogenesis and differentiation in adult humans
A novel cardiomyogenic role for Isl1 <sup>+</sup> neural crest cells in the inflow tract
BAP1 regulates epigenetic switch from pluripotency to differentiation in developmental lineages giving rise to BAP1-mutant cancers
Punctuated evolution of canonical genomic aberrations in uveal melanoma
Drug and disease signature integration identifies synergistic combinations in glioblastoma
Gain of function of ASXL1 truncating protein in the pathogenesis of myeloid malignancies
Epigenetic reprogramming and aberrant expression of PRAME are associated with increased metastatic risk in Class 1 and Class 2 uveal melanomas
Cytoplasmic p27 promotes epithelial–mesenchymal transition and tumor metastasis via STAT3-mediated Twist1 upregulation
Conversion Strategy Using an Expanded Genetic Alphabet to Assay Nucleic Acids