Area of research
Cancer Research · Genetics
Research interest
Research interests include Chemistry, Hypoxia (environmental), Microglia, Mitochondrion, Medicine, and Pharmacology.
Pharmacological Inhibition of Mitochondrial Division Attenuates Simulated High‐Altitude Exposure‐Induced Memory Impairment in Mice: Involvement of Inhibition of Microglia‐Mediated Synapse Elimination
CX3CL1/CX3CR1 signal mediates M1-type microglia and accelerates high-altitude-induced forgetting
Intermittent hypoxia therapy ameliorates beta-amyloid pathology via TFEB-mediated autophagy in murine Alzheimer's disease
Caveolin-1 accelerates hypoxia-induced endothelial dysfunction in high-altitude cerebral edema
NRF1-mediated microglial activation triggers high-altitude cerebral edema
Pharmacological inhibition of mitochondrial division attenuates simulated high-altitude exposure-induced cerebral edema in mice: Involvement of inhibition of the NF-κB signaling pathway in glial cells
Testosterone attenuates hypoxia-induced hypertension by affecting NRF1-mediated transcriptional regulation of ET-1 and ACE
Intermittent hypoxia preconditioning protects WRL68 cells against oxidative injury: Involvement of the PINK1/Parkin-mediated mitophagy regulated by nuclear respiratory factor 1
Synthesis and evaluation of diphyllin β‐hydroxyl amino derivatives as novel V‐ATPase inhibitors
Inhibition of Aβ aggregates in Alzheimer’s disease by epigallocatechin and epicatechin-3-gallate from green tea
Fasting Increases Iron Export by Modulating Ferroportin 1 Expression Through the Ghrelin/GHSR1α/MAPK Pathway in the Liver
2, 4, 5-Trideoxyhexopyranosides Derivatives of 4’-Demethylepipodophyllotoxin: De novo Synthesis and Anticancer Activity
Positive regulation of human PINK1 and Parkin gene expression by nuclear respiratory factor 1
Development of β-elemene and Cisplatin Co-Loaded Liposomes for Effective Lung Cancer Therapy and Evaluation in Patient-Derived Tumor Xenografts
Ammonia mediates mitochondrial uncoupling and promotes glycolysis via HIF-1 activation in human breast cancer MDA-MB-231 cells
Transcription regulation of NRF1 on StAR reduces testosterone synthesis in hypoxemic murine
Brusatol Protects HepG2 Cells against Oxygen-Glucose Deprivation-Induced Injury via Inhibiting Mitochondrial Reactive Oxygen Species-Induced Oxidative Stress
Divergent <i>De Novo</i> Synthesis of 2,4,5-trideoxyhexopyranosides Derivatives of Podophyllotoxin as Anticancer Agents
Cleistanthin A inhibits the invasion of MDA-MB-231 human breast cancer cells: involvement of the β-catenin pathway
The roles of hypoxia-inducible Factor-1 and iron regulatory protein 1 in iron uptake induced by acute hypoxia
HIF 1 inhibits STAR transcription and testosterone synthesis in murine Leydig cells
Hypoxia inducible factor 1α in hepatocellular carcinoma with cirrhosis: Association with prognosis
Asiatic acid ameliorates hepatic ischemia/reperfusion injury in rats via mitochondria-targeted protective mechanism
Hypoxia reduces testosterone synthesis in mouse Leydig cells by inhibiting NRF1-activated StAR expression
Brusatol inhibits HIF-1 signaling pathway and suppresses glucose uptake under hypoxic conditions in HCT116 cells
Asiatic acid uncouples respiration in isolated mouse liver mitochondria and induces HepG2 cells death
Nuclear respiratory factor‐1 (NRF‐1) regulated hypoxia‐inducible factor‐1α (HIF‐1α) under hypoxia in HEK293T
ZT-25, a new vacuolar H+-ATPase inhibitor, induces apoptosis and protective autophagy through ROS generation in HepG2 cells
Two macrocyclic polyamines as modulators of metal-mediated Aβ<sub>40</sub>aggregation
Synthesis and Evaluation of Cleistanthin A Derivatives as Potent Vacuolar H<sup>+</sup>‐ATPase Inhibitors