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Yapeng Lu

Jiangsu University · CN
Area of research
Cancer Research · Genetics
Research interest
Research interests include Chemistry, Hypoxia (environmental), Microglia, Mitochondrion, Medicine, and Pharmacology.
h-index
citations
1,253
works
39
NIH funding
primary concept
email

Recent publications

Pharmacological Inhibition of Mitochondrial Division Attenuates Simulated High‐Altitude Exposure‐Induced Memory Impairment in Mice: Involvement of Inhibition of Microglia‐Mediated Synapse Elimination
CNS Neuroscience & Therapeutics 2025cited by 3position: middledoi
CX3CL1/CX3CR1 signal mediates M1-type microglia and accelerates high-altitude-induced forgetting
Frontiers in Cellular Neuroscience 2023cited by 29position: middledoi
Intermittent hypoxia therapy ameliorates beta-amyloid pathology via TFEB-mediated autophagy in murine Alzheimer's disease
Journal of Neuroinflammation 2023cited by 29position: middledoi
Caveolin-1 accelerates hypoxia-induced endothelial dysfunction in high-altitude cerebral edema
Cell Communication and Signaling 2022cited by 65position: middledoi
NRF1-mediated microglial activation triggers high-altitude cerebral edema
Journal of Molecular Cell Biology 2022cited by 52position: middledoi
Pharmacological inhibition of mitochondrial division attenuates simulated high-altitude exposure-induced cerebral edema in mice: Involvement of inhibition of the NF-κB signaling pathway in glial cells
European Journal of Pharmacology 2022cited by 19position: firstdoi
Testosterone attenuates hypoxia-induced hypertension by affecting NRF1-mediated transcriptional regulation of ET-1 and ACE
Hypertension Research 2021cited by 25position: middledoi
Intermittent hypoxia preconditioning protects WRL68 cells against oxidative injury: Involvement of the PINK1/Parkin-mediated mitophagy regulated by nuclear respiratory factor 1
Mitochondrion 2021cited by 9position: firstdoi
Synthesis and evaluation of diphyllin β‐hydroxyl amino derivatives as novel V‐ATPase inhibitors
Chemical Biology & Drug Design 2021cited by 6position: middledoi
Inhibition of Aβ aggregates in Alzheimer’s disease by epigallocatechin and epicatechin-3-gallate from green tea
Bioorganic Chemistry 2020cited by 55position: middledoi
Fasting Increases Iron Export by Modulating Ferroportin 1 Expression Through the Ghrelin/GHSR1α/MAPK Pathway in the Liver
Biological Trace Element Research 2020cited by 9position: middledoi
2, 4, 5-Trideoxyhexopyranosides Derivatives of 4’-Demethylepipodophyllotoxin: De novo Synthesis and Anticancer Activity
Medicinal Chemistry 2020cited by 8position: firstdoi
Positive regulation of human PINK1 and Parkin gene expression by nuclear respiratory factor 1
Mitochondrion 2019cited by 38position: firstdoi
Development of β-elemene and Cisplatin Co-Loaded Liposomes for Effective Lung Cancer Therapy and Evaluation in Patient-Derived Tumor Xenografts
Pharmaceutical Research 2019cited by 28position: middledoi
Ammonia mediates mitochondrial uncoupling and promotes glycolysis via HIF-1 activation in human breast cancer MDA-MB-231 cells
Biochemical and Biophysical Research Communications 2019cited by 21position: firstdoi
Transcription regulation of NRF1 on StAR reduces testosterone synthesis in hypoxemic murine
The Journal of Steroid Biochemistry and Molecular Biology 2019cited by 20position: middledoi
Brusatol Protects HepG2 Cells against Oxygen-Glucose Deprivation-Induced Injury via Inhibiting Mitochondrial Reactive Oxygen Species-Induced Oxidative Stress
Pharmacology 2019cited by 12position: lastdoi
Divergent <i>De Novo</i> Synthesis of 2,4,5-trideoxyhexopyranosides Derivatives of Podophyllotoxin as Anticancer Agents
Future Medicinal Chemistry 2019cited by 10position: firstdoi
Cleistanthin A inhibits the invasion of MDA-MB-231 human breast cancer cells: involvement of the β-catenin pathway
Pharmacological Reports 2019cited by 10position: middledoi
The roles of hypoxia-inducible Factor-1 and iron regulatory protein 1 in iron uptake induced by acute hypoxia
Biochemical and Biophysical Research Communications 2018cited by 51position: middledoi
HIF 1 inhibits STAR transcription and testosterone synthesis in murine Leydig cells
Journal of Molecular Endocrinology 2018cited by 42position: middledoi
Hypoxia inducible factor 1α in hepatocellular carcinoma with cirrhosis: Association with prognosis
Pathology - Research and Practice 2018cited by 28position: middledoi
Asiatic acid ameliorates hepatic ischemia/reperfusion injury in rats via mitochondria-targeted protective mechanism
Toxicology and Applied Pharmacology 2017cited by 39position: firstdoi
Hypoxia reduces testosterone synthesis in mouse Leydig cells by inhibiting NRF1-activated StAR expression
Oncotarget 2017cited by 35position: middledoi
Brusatol inhibits HIF-1 signaling pathway and suppresses glucose uptake under hypoxic conditions in HCT116 cells
Scientific Reports 2016cited by 66position: firstdoi
Asiatic acid uncouples respiration in isolated mouse liver mitochondria and induces HepG2 cells death
European Journal of Pharmacology 2016cited by 35position: firstdoi
Nuclear respiratory factor‐1 (NRF‐1) regulated hypoxia‐inducible factor‐1α (HIF‐1α) under hypoxia in HEK293T
IUBMB Life 2016cited by 34position: middledoi
ZT-25, a new vacuolar H+-ATPase inhibitor, induces apoptosis and protective autophagy through ROS generation in HepG2 cells
European Journal of Pharmacology 2015cited by 49position: firstdoi
Two macrocyclic polyamines as modulators of metal-mediated Aβ<sub>40</sub>aggregation
Integrative Biology 2015cited by 22position: middledoi
Synthesis and Evaluation of Cleistanthin A Derivatives as Potent Vacuolar H<sup>+</sup>‐ATPase Inhibitors
Chemical Biology & Drug Design 2015cited by 22position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Li Zhu · Nantong University26 papers (2012–2025)Xueting Wang · Guiyang Medical University14 papers (2016–2023)Qianqian Luo · Fudan University12 papers (2015–2025)Yu Zhao · Nantong University8 papers (2012–2021)Wangwang Ding · Nantong University6 papers (2019–2022)Li Zhu · Nantong University6 papers (2015–2021)Xiaomei Wu · South China Agricultural University5 papers (2012–2022)Lu Wang · Nantong University4 papers (2019–2019)Shajun Zhu · Nantong University4 papers (2012–2020)Peng Zhao · Nantong University3 papers (2012–2014)Dan Wang · King University3 papers (2019–2023)Xueting Wang · Fudan University3 papers (2019–2023)Bin Peng · Nantong University3 papers (2012–2013)Dan Wang · University of Science and Technology of China3 papers (2019–2022)Zhangji Dong · Nantong University3 papers (2017–2022)Jiangpei Bian · Nantong University3 papers (2021–2025)Huiwen Kan · Nantong University3 papers (2017–2021)Jing Gao · Jiangsu University3 papers (2015–2017)Baolan Wan · Nantong University3 papers (2022–2023)Guijuan Chen · Nantong University3 papers (2021–2023)