Area of research
Neurology · Genetics
Research interest
Research interests include Neuroinflammation and Neurodegeneration Mechanisms, High Altitude and Hypoxia, Cancer, Hypoxia, and Metabolism, and Adipose Tissue and Metabolism.
Vitamin D receptor agonists inhibit liver fibrosis by disrupting the interaction between hepatic stellate cells and neutrophil extracellular traps
VPS35-Retromer: Multifunctional Roles in Various Biological Processes – A Focus on Neurodegenerative Diseases and Cancer
Hydroxychloroquine Prevents High-altitude Cerebral Edema by Inhibiting Endothelial Claudin-5 Autophagic Degradation
Pro-Inflammatory Microglia Exacerbate High-Altitude-Induced Cognitive Impairment by Driving Lipid Droplet Accumulation in Astrocytes
Intermittent hypoxia exacerbates anxiety in high-fat diet-induced diabetic mice by inhibiting TREM2-regulated IFNAR1 signaling
Intermittent hypoxia training enhances Aβ endocytosis by plaque associated microglia via VPS35-dependent TREM2 recycling in murine Alzheimer’s disease
CX3CL1/CX3CR1 signal mediates M1-type microglia and accelerates high-altitude-induced forgetting
Effective drug and shRNA delivery for synergistic treatment of triple-negative breast cancer by sequentially targeting tumor hypoxia
Caveolin-1 accelerates hypoxia-induced endothelial dysfunction in high-altitude cerebral edema
NRF1-mediated microglial activation triggers high-altitude cerebral edema
Argon mitigates post-stroke neuroinflammation by regulating M1/M2 polarization and inhibiting NF-<b>κ</b>B/NLRP3 inflammasome signaling
(−)-Epicatechin gallate prevents inflammatory response in hypoxia-activated microglia and cerebral edema by inhibiting NF-κB signaling
Pharmacological inhibition of mitochondrial division attenuates simulated high-altitude exposure-induced cerebral edema in mice: Involvement of inhibition of the NF-κB signaling pathway in glial cells
Joining Forces for Cancer Treatment: From “TCR versus CAR” to “TCR and CAR”
Transcriptional regulation of NRF1 on metabotropic glutamate receptors in a neonatal hypoxic‑ischemic encephalopathy rat model
AD-linked R47H-<i>TREM2</i>mutation induces disease-enhancing microglial states via AKT hyperactivation
Alendronate-functionalized hypoxia-responsive polymeric micelles for targeted therapy of bone metastatic prostate cancer
Testosterone attenuates hypoxia-induced hypertension by affecting NRF1-mediated transcriptional regulation of ET-1 and ACE
Testosterone attenuates pulmonary epithelial inflammation in male rats of COPD model through preventing NRF1-derived NF-κB signaling
Ammonia mediates mitochondrial uncoupling and promotes glycolysis via HIF-1 activation in human breast cancer MDA-MB-231 cells
Transcription regulation of NRF1 on StAR reduces testosterone synthesis in hypoxemic murine
Cleistanthin A inhibits the invasion of MDA-MB-231 human breast cancer cells: involvement of the β-catenin pathway
The roles of hypoxia-inducible Factor-1 and iron regulatory protein 1 in iron uptake induced by acute hypoxia
HIF 1 inhibits STAR transcription and testosterone synthesis in murine Leydig cells
Hypoxia inducible factor 1α in hepatocellular carcinoma with cirrhosis: Association with prognosis
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9‐mediated <i>kif15</i> mutations accelerate axonal outgrowth during neuronal development and regeneration in zebrafish
Asiatic acid ameliorates hepatic ischemia/reperfusion injury in rats via mitochondria-targeted protective mechanism
Hypoxia reduces testosterone synthesis in mouse Leydig cells by inhibiting NRF1-activated StAR expression
Brusatol inhibits HIF-1 signaling pathway and suppresses glucose uptake under hypoxic conditions in HCT116 cells
Neferine prevented hyperglycemia-induced endothelial cell apoptosis through suppressing ROS/Akt/NF-κB signal
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