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P. Darrell Neufer

Wake Forest University · US
Area of research
Molecular Biology · Physiology
Research interest
Research interests include Adipose Tissue and Metabolism, Mitochondrial Function and Pathology, Muscle metabolism and nutrition, and Muscle Physiology and Disorders.
h-index
68
citations
15,202
works
210
NIH funding
primary concept
email

Recent publications

eLife Assessment: Suppression of interferon signaling via small molecule modulation of TFAM
2025cited by 0position: contributordoi
High-dose atorvastatin therapy progressively decreases skeletal muscle mitochondrial respiratory capacity in humans
JCI Insight 2024cited by 19position: contributordoi
Skeletal Muscle Mitochondrial Respiration and Exercise Intolerance in Patients With Heart Failure With Preserved Ejection Fraction
JAMA Cardiology 2023cited by 93position: middledoi
Human studies of mitochondrial biology demonstrate an overall lack of binary sex differences: A multivariate meta‐analysis
The FASEB Journal 2022cited by 64position: middledoi
From OCR and ECAR to energy: Perspectives on the design and interpretation of bioenergetics studies
Journal of Biological Chemistry 2021cited by 160position: contributordoi
Genetically increasing flux through β-oxidation in skeletal muscle increases mitochondrial reductive stress and glucose intolerance
American Journal of Physiology-Endocrinology and Metabolism 2021cited by 26position: contributordoi
Aglycemic growth enhances carbohydrate metabolism and induces sensitivity to menadione in cultured tumor-derived cells
Cancer & Metabolism 2021cited by 10position: contributordoi
Reply to Figueira et al.: Can NAD(P)+ transhydrogenase (NNT) mediate a physiologically meaningful increase in energy expenditure by mitochondria during H2O2 removal?
Journal of Biological Chemistry 2021cited by 3position: contributordoi
Intrinsic OXPHOS limitations underlie cellular bioenergetics in leukemia.
2021cited by 1position: contributordoi
PFKFB3-mediated glycolysis rescues myopathic outcomes in the ischemic limb
JCI Insight 2020cited by 37position: contributordoi
Flux through mitochondrial redox circuits linked to nicotinamide nucleotide transhydrogenase generates counterbalance changes in energy expenditure
Journal of Biological Chemistry 2020cited by 35position: contributordoi
Intrinsic oxidative phosphorylation limitations underlie cellular bioenergetics in leukemia.
2020cited by 2position: contributordoi
Mitochondrial PE potentiates respiratory enzymes to amplify skeletal muscle aerobic capacity
Science Advances 2019cited by 100position: middledoi
Mitochondrial PE potentiates respiratory enzymes to amplify skeletal muscle aerobic capacity.
2019cited by 88position: contributordoi
Phospholipid methylation regulates muscle metabolic rate through Ca2+ transport efficiency
Nature Metabolism 2019cited by 46position: middledoi
Phospholipid methylation regulates muscle metabolic rate through Ca<sup>2+</sup> transport efficiency.
2019cited by 37position: contributordoi
Overexpression of Long-Chain Acyl-CoA Synthetase 5 Increases Fatty Acid Oxidation and Free Radical Formation While Attenuating Insulin Signaling in Primary Human Skeletal Myotubes
International Journal of Environmental Research and Public Health 2019cited by 21position: middledoi
Alternative splicing of UCP1 by non-cell-autonomous action of PEMT
Molecular Metabolism 2019cited by 20position: middledoi
Cutting fuel offers new clues in diabetic mystery
Journal of Biological Chemistry 2019cited by 6position: contributordoi
Targeted overexpression of catalase to mitochondria does not prevent cardioskeletal myopathy in Barth syndrome
Journal of Molecular and Cellular Cardiology 2018cited by 69position: middledoi
Understanding the Cellular and Molecular Mechanisms of Physical Activity-Induced Health Benefits
Cell Metabolism 2015cited by 485position: firstdoi
Targeted Metabolomics Connects Thioredoxin-interacting Protein (TXNIP) to Mitochondrial Fuel Selection and Regulation of Specific Oxidoreductase Enzymes in Skeletal Muscle
Journal of Biological Chemistry 2014cited by 64position: middledoi
Exercise Biology and Medicine: Innovative Research to Improve Global Health
Mayo Clinic Proceedings 2014cited by 48position: middledoi
Methods for Assessing Mitochondrial Function in Diabetes
Diabetes 2013cited by 169position: lastdoi
Submaximal ADP‐stimulated respiration is impaired in ZDF rats and recovered by resveratrol
The Journal of Physiology 2013cited by 36position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

· 13 papers (2019–2025)Christopher G. R. Perry · York University3 papers (2013–2014)Kelsey H Fisher-Wellman · Atrium Health Wake Forest Baptist3 papers (2020–2021)Terence E Ryan · University of Florida3 papers (2019–2024)Anthony R.P. Verkerke · Beth Israel Deaconess Medical Center3 papers (2018–2019)Katsuhiko Funai · University of Utah3 papers (2018–2019)Jordan M. Johnson · Utah State University3 papers (2018–2019)Patrick J. Ferrara · Regeneron (United States)3 papers (2018–2019) · 2 papers (2018–2019)Cody D. Smith · East Carolina University2 papers (2020–2021)Katsuhiko Funai · Institute of Nutrition, Metabolism and Diabetes2 papers (2019–2019) · 2 papers (2018–2019)Anthony Molina · University of California San Diego2 papers (2022–2023)J. Alan Maschek · University of Utah2 papers (2019–2019)Chien‐Te Lin · Wake Forest University2 papers (2019–2019)James E. Cox · University of Utah2 papers (2019–2019) · 1 papers (2013–2013)Julie H. Cox · Southwestern Medical Center1 papers (2019–2019)Daniel S. Lark · Colorado State University1 papers (2014–2014)M. Benjamin Nelson · Ball State University1 papers (2023–2023)