Area of research
Genetics · Molecular Biology
Research interest
Research interests include Glioma Diagnosis and Treatment, Cancer Genomics and Diagnostics, Epigenetics and DNA Methylation, and Hedgehog Signaling Pathway Studies.
ZIC1 is a context-dependent medulloblastoma driver in the rhombic lip
Failure of human rhombic lip differentiation underlies medulloblastoma formation
Author Correction: Failure of human rhombic lip differentiation underlies medulloblastoma formation
The transcriptional landscape of Shh medulloblastoma
Locoregional delivery of CAR T cells to the cerebrospinal fluid for treatment of metastatic medulloblastoma and ependymoma
Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma
Childhood cerebellar tumours mirror conserved fetal transcriptional programs
Recurrent noncoding U1 snRNA mutations drive cryptic splicing in SHH medulloblastoma
Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis
A Hematogenous Route for Medulloblastoma Leptomeningeal Metastases
Heterogeneity within the PF-EPN-B ependymoma subgroup
A Novel Method for Rapid Molecular Subgrouping of Medulloblastoma
EPEN-28. HETEROGENEITY WITHIN THE PFB EPENDYMOMA SUBGROUP
Intertumoral Heterogeneity within Medulloblastoma Subgroups
The whole-genome landscape of medulloblastoma subtypes
Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy
Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling
Spatial heterogeneity in medulloblastoma
Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis
Divergent clonal selection dominates medulloblastoma at recurrence
Medulloblastoma subgroups remain stable across primary and metastatic compartments
Cytogenetic Prognostication Within Medulloblastoma Subgroups
Recurrence patterns across medulloblastoma subgroups: an integrated clinical and molecular analysis
TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma
Subgroup-specific structural variation across 1,000 medulloblastoma genomes