Area of research
Genetics · Cancer Research
Research interest
Research interests include Glioma Diagnosis and Treatment, Cancer Genomics and Diagnostics, Epigenetics and DNA Methylation, and FOXO transcription factor regulation.
A microenvironment-determined risk continuum refines subtyping in meningioma and reveals determinants of machine learning-based tumor classification
Explainable artificial intelligence of DNA methylation-based brain tumor diagnostics
Advancing CNS tumor diagnostics with expanded DNA methylation-based classification
CEBPA repression by MECOM blocks differentiation to drive aggressive leukemias
Cellular hierarchies of embryonal tumors with multilayered rosettes are shaped by oncogenic microRNAs and receptor–ligand interactions
Advancing CNS tumor diagnostics with expanded DNA methylation-based classification
In silico purification improves DNA methylation-based classification rates of pediatric low-grade gliomas
Conumee 2.0: enhanced copy-number variation analysis from DNA methylation arrays for humans and mice
A prognostic neural epigenetic signature in high-grade glioma
Loss over 5% of chromosome 1p is a clinically relevant and applicable cut-off for increased risk of recurrence in meningioma
Cell-state plasticity drives heterogeneity in Group 3/4 medulloblastoma
Pipeline Olympics: continuable benchmarking of computational workflows for DNA methylation sequencing data against an experimental gold standard
Multiomic neuropathology improves diagnostic accuracy in pediatric neuro-oncology
Mapping pediatric brain tumors to their origins in the developing cerebellum
Epigenetic neural glioblastoma enhances synaptic integration and predicts therapeutic vulnerability
Author Correction: Multiomic neuropathology improves diagnostic accuracy in pediatric neuro-oncology
FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits
Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing
Sarcoma classification by DNA methylation profiling
Mutational mechanisms shaping the coding and noncoding genome of germinal center derived B-cell lymphomas
Integrated phospho-proteogenomic and single-cell transcriptomic analysis of meningiomas establishes robust subtyping and reveals subtype-specific immune invasion
Mapping pediatric brain tumors to their origins in the developing cerebellum
Single-Cell RNA-Seq Reveals Cellular Hierarchies and Impaired Developmental Trajectories in Pediatric Ependymoma
Machine learning workflows to estimate class probabilities for precision cancer diagnostics on DNA methylation microarray data
Abstract B27: A link between small noncoding RNAs and mRNA translation elongation: The let7-eEF2K axis in pediatric tumor adaptation to nutrient deprivation
Abstract B73: Second-generation molecular subgrouping of medulloblastoma: An international meta-analysis of Group 3 and Group 4 subtypes
ETMR-17. SINGLE-CELL TRANSCRIPTOME ANALYSIS OF ETMR PATIENT SAMPLES
EPEN-21. IMPAIRED NEURONAL-GLIAL FATE SPECIFICATION IN PEDIATRIC EPENDYMOMA REVEALED BY SINGLE-CELL RNA-SEQ
Single-Cell RNA-Seq Reveals AML Hierarchies Relevant to Disease Progression and Immunity
Resolving medulloblastoma cellular architecture by single-cell genomics