Area of research
Molecular Biology
Research interest
Research interests include DNA Repair Mechanisms, Genomics and Chromatin Dynamics, CRISPR and Genetic Engineering, and Cancer therapeutics and mechanisms.
Reconstitution of SPO11-dependent double-strand break formation
Mouse MRE11-RAD50-NBS1 is needed to start and extend meiotic DNA end resection
ATM suppresses c-Myc overexpression in the mammary epithelium in response to estrogen
ATM and PRDM9 regulate SPO11-bound recombination intermediates during meiosis
BRCA1 ensures genome integrity by eliminating estrogen-induced pathological topoisomerase II–DNA complexes
A global view of meiotic double-strand break end resection
Genomic and chromatin features shaping meiotic double-strand break formation and repair in mice
The Landscape of Mouse Meiotic Double-Strand Break Formation, Processing, and Repair