Area of research
Molecular Biology · Physiology
Research interest
Research interests include Adipose Tissue and Metabolism, Metabolism, Diabetes, and Cancer, Metabolomics and Mass Spectrometry Studies, and Bioinformatics and Genomic Networks.
Maturation of human cardiac organoids enables complex disease modeling and drug discovery
Phosphoproteomics reveals rewiring of the insulin signaling network and multi-nodal defects in insulin resistance
Gut-derived acetate promotes B10 cells with antiinflammatory effects
Dissecting the biology of mTORC1 beyond rapamycin
Is Mitochondrial Dysfunction a Common Root of Noncommunicable Chronic Diseases?
Insulin signaling requires glucose to promote lipid anabolism in adipocytes
Lipid and glucose metabolism in hepatocyte cell lines and primary mouse hepatocytes: a comprehensive resource for in vitro studies of hepatic metabolism
Lactate production is a prioritized feature of adipocyte metabolism
Serine 474 phosphorylation is essential for maximal Akt2 kinase activity in adipocytes
Mitochondrial oxidants, but not respiration, are sensitive to glucose in adipocytes
Muscle and adipose tissue insulin resistance: malady without mechanism?
Mitochondrial CoQ deficiency is a common driver of mitochondrial oxidants and insulin resistance
Mitochondrial oxidative stress causes insulin resistance without disrupting oxidative phosphorylation
High dietary fat and sucrose result in an extensive and time-dependent deterioration in health of multiple physiological systems in mice
Benzylserine inhibits breast cancer cell growth by disrupting intracellular amino acid homeostasis and triggering amino acid response pathways
Dynamic Metabolomics Reveals that Insulin Primes the Adipocyte for Glucose Metabolism
Defining the Nutritional and Metabolic Context of FGF21 Using the Geometric Framework
14-3-3ζ regulates the mitochondrial respiratory reserve linked to platelet phosphatidylserine exposure and procoagulant function
mTORC2 and AMPK differentially regulate muscle triglyceride content via Perilipin 3
Kinome Screen Identifies PFKFB3 and Glucose Metabolism as Important Regulators of the Insulin/Insulin-like Growth Factor (IGF)-1 Signaling Pathway
Proteomic Analysis of GLUT4 Storage Vesicles Reveals Tumor Suppressor Candidate 5 (TUSC5) as a Novel Regulator of Insulin Action in Adipocytes
Acute mTOR inhibition induces insulin resistance and alters substrate utilization in vivo