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Sandra O. Tomé

Allen Institute for Brain Science · US
Area of research
Physiology · Neurology
Research interest
Research interests include Alzheimer's disease research and treatments, Dementia and Cognitive Impairment Research, Parkinson's Disease Mechanisms and Treatments, and Amyotrophic Lateral Sclerosis Research.
h-index
16
citations
957
works
48
NIH funding
primary concept
email

Recent publications

Differences and overlaps in TDP-43 pathology of ‘pure’ LATE-NC compared to LATE-NC coexisting with Alzheimer’s disease
Acta Neuropathologica 2025cited by 3position: firstdoi
Specific atrophy patterns distinguish tau and TDP-43 pathology: a longitudinal MRI ante-mortem study
Acta Neuropathologica Communications 2025cited by 3position: middledoi
Tracing neuropathological signatures: <i>TARDBP</i> and <i>C9orf72</i> double mutations in a Sicilian family
Human Molecular Genetics 2025cited by 1position: middledoi
Tau pathology in the retina and its role in neurodegeneration
Alzheimer s & Dementia 2025cited by 1position: middledoi
The Olfactory Epithelium: A Critical Gateway for Pathological Tau Propagation and a Target for Mitigating Tauopathy in the Central Nervous System
bioRxiv (Cold Spring Harbor Laboratory) 2025cited by 0position: middledoi
Amygdala-predominant α-synuclein pathology is associated with exacerbated hippocampal neuron loss in Alzheimer’s disease
Brain Communications 2024cited by 17position: middledoi
Pure LATE-NC: Frequency, clinical impact, and the importance of considering APOE genotype when assessing this and other subtypes of non-Alzheimer’s pathologies
Acta Neuropathologica 2024cited by 14position: middledoi
Hypothesis-based investigation of known AD risk variants reveals the genetic underpinnings of neuropathological lesions observed in Alzheimer’s-type dementia
Acta Neuropathologica 2024cited by 4position: middledoi
TDP-43 pathology is associated with increased tau burdens and seeding
Molecular Neurodegeneration 2023cited by 63position: firstdoi
<scp>LATE‐NC</scp> in <scp>Alzheimer's</scp> disease: <scp>Molecular</scp> aspects and synergies
Brain Pathology 2023cited by 16position: firstdoi
The impact of co‐morbid LATE‐NC pathology in Alzheimer’s Disease.
Alzheimer s & Dementia 2023cited by 0position: firstdoi
Association of hippocampal neuron loss, pTDP‐43, and Alzheimer’s disease pathology with the presence of cerebral Lewy bodies
Alzheimer s & Dementia 2023cited by 0position: middledoi
LATE-NC staging in routine neuropathologic diagnosis: an update
Acta Neuropathologica 2022cited by 172position: middledoi
The central role of tau in Alzheimer’s disease: From neurofibrillary tangle maturation to the induction of cell death
Brain Research Bulletin 2022cited by 81position: lastdoi
Increased pyroptosis activation in white matter microglia is associated with neuronal loss in ALS motor cortex
Acta Neuropathologica 2022cited by 54position: middledoi
LATE-NC aggravates GVD-mediated necroptosis in Alzheimer’s disease
Acta Neuropathologica Communications 2022cited by 36position: middledoi
Neuronal loss of the nucleus basalis of Meynert in primary progressive aphasia is associated with Alzheimer's disease neuropathological changes
Alzheimer s & Dementia 2022cited by 4position: middledoi
Maturation of neuronal AD-tau pathology involves site-specific phosphorylation of cytoplasmic and synaptic tau preceding conformational change and fibril formation
Acta Neuropathologica 2021cited by 78position: middledoi
TDP-43 interacts with pathological τ protein in Alzheimer’s disease
Acta Neuropathologica 2021cited by 53position: firstdoi
Co-pathologies in Alzheimer’s disease: just multiple pathologies or partners in crime?
Brain 2021cited by 35position: firstdoi
Distinct molecular patterns of TDP-43 pathology in Alzheimer’s disease: relationship with clinical phenotypes
Acta Neuropathologica Communications 2020cited by 108position: firstdoi
Necrosome‐positive granulovacuolar degeneration is associated with TDP‐43 pathological lesions in the hippocampus of ALS/FTLD cases
Neuropathology and Applied Neurobiology 2020cited by 31position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Dietmar Rudolf Thal · KU Leuven20 papers (2020–2025)Rik Vandenberghe · Allen Institute for Brain Science12 papers (2020–2025)Simona Ospitalieri · Neuroelectronics Research Flanders10 papers (2020–2025)Markus Otto · University Hospital in Halle10 papers (2020–2025)Alicja Ronisz · Neuroelectronics Research Flanders9 papers (2022–2025)Christine A. F. Von Arnim · Ludwig-Maximilians-Universität München8 papers (2020–2025)Klara Gawor · Allen Institute for Brain Science8 papers (2022–2025)Philip Van Damme · Universitair Ziekenhuis Leuven5 papers (2020–2024)Evelien Van Schoor · Allen Institute for Brain Science4 papers (2020–2022)Estifanos Ghebremedhin · Goethe University Frankfurt4 papers (2022–2025)Mathieu Vandenbulcke · Allen Institute for Brain Science3 papers (2021–2024)Thomas Tousseyn · Catholic University of America3 papers (2020–2021)Celeste Laureyssen · University of Antwerp3 papers (2023–2025)Kristel Sleegers · Oslo University Hospital3 papers (2023–2025)Joost Schymkowitz · VIB-KU Leuven Center for Cancer Biology3 papers (2023–2025)Luis Aragão Gomes · Allen Institute for Brain Science3 papers (2021–2023)Ludo Van Den Bosch · Allen Institute for Brain Science3 papers (2020–2023)Grigoria Tsaka · VIB-KU Leuven Center for Cancer Biology3 papers (2023–2025)Matthew B. Blaschko · KU Leuven2 papers (2022–2024)Jolien Schaeverbeke · VIB-KU Leuven Center for Brain & Disease Research2 papers (2022–2022)