Area of research
Neurology · Physiology
Research interest
Research interests include Amyotrophic Lateral Sclerosis Research, Alzheimer's disease research and treatments, Neurogenetic and Muscular Disorders Research, and Mitochondrial Function and Pathology.
<i>C21ORF2</i> mutations point towards primary cilia dysfunction in amyotrophic lateral sclerosis
Correction: Pyroptosis in Alzheimer’s disease: cell type‑specific activation in microglia, astrocytes and neurons
A toxic gain-of-function mechanism in C9orf72 ALS impairs the autophagy-lysosome pathway in neurons
Pyroptosis in Alzheimer’s disease: cell type-specific activation in microglia, astrocytes and neurons
Increased pyroptosis activation in white matter microglia is associated with neuronal loss in ALS motor cortex
LATE-NC aggravates GVD-mediated necroptosis in Alzheimer’s disease
CRISPR/Cas9 screen in human iPSC‐derived cortical neurons identifies NEK6 as a novel disease modifier of <i>C9orf72</i> poly(PR) toxicity
HNRNPK alleviates RNA toxicity by counteracting DNA damage in C9orf72 ALS
Distinct molecular patterns of TDP-43 pathology in Alzheimer’s disease: relationship with clinical phenotypes
Necrosome‐positive granulovacuolar degeneration is associated with TDP‐43 pathological lesions in the hippocampus of ALS/FTLD cases
Dipeptide repeat protein and TDP-43 pathology along the hypothalamic–pituitary axis in C9orf72 and non-C9orf72 ALS and FTLD-TDP cases
Necrosome complex detected in granulovacuolar degeneration is associated with neuronal loss in Alzheimer’s disease
TSPO Versus P2X7 as a Target for Neuroinflammation: An In Vitro and In Vivo Study
Circadian sleep/wake-associated cells show dipeptide repeat protein aggregates in C9orf72-related ALS and FTLD cases
An ALS case with 38 (G4C2)-repeats in the C9orf72 gene shows TDP-43 and sparse dipeptide repeat protein pathology