Area of research
Molecular Biology · Plant Science
Research interest
Research interests include Biology, Reprogramming, Cell biology, Somatic cell, Chromatin, and RNA.
A spatiotemporal atlas of mouse liver homeostasis and regeneration
Single‐cell RNA sequencing reveals immune cell dysfunction in the peripheral blood of patients with highly aggressive gastric cancer
A primate-specific endogenous retroviral envelope protein sequesters SFRP2 to regulate human cardiomyocyte development
c-JUN is a barrier in hESC to cardiomyocyte transition
CTCF functions as an insulator for somatic genes and a chromatin remodeler for pluripotency genes during reprogramming
Metabolic and epigenetic dysfunctions underlie the arrest of in vitro fertilized human embryos in a senescent-like state
Pluripotency reprogramming by competent and incompetent POU factors uncovers temporal dependency for Oct4 and Sox2
Capturing the interactome of newly transcribed RNA
Transposable elements are regulated by context-specific patterns of chromatin marks in mouse embryonic stem cells
Resolution of Reprogramming Transition States by Single Cell RNA-Sequencing
The p53-induced lincRNA-p21 derails somatic cell reprogramming by sustaining H3K9me3 and CpG methylation at pluripotency gene promoters
Transcriptional Pause Release Is a Rate-Limiting Step for Somatic Cell Reprogramming
Genome of Acanthamoeba castellanii highlights extensive lateral gene transfer and early evolution of tyrosine kinase signaling
Oct4 switches partnering from Sox2 to Sox17 to reinterpret the enhancer code and specify endoderm