Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include Biology, Cell biology, Reprogramming, Embryonic stem cell, Somatic cell, and Stem cell.
Scalable modulation of CRISPR‒Cas enzyme activity using photocleavable phosphorothioate DNA
A complete model of mouse embryogenesis through organogenesis enabled by chemically induced embryo founder cells
Human embryo research: how to move towards a 28-day limit
Bardoxolone methyl blocks the efflux of Zn2+ by targeting hZnT1 to inhibit the proliferation and metastasis of cervical cancer
Structure-guided screening identifies Tucatinib as dual inhibitor for MCT1/2
Inhibition of HDAC activity directly reprograms murine embryonic stem cells to trophoblast stem cells
Activation mechanisms of dimeric mechanosensitive OSCA/TMEM63 channels
A primate-specific endogenous retroviral envelope protein sequesters SFRP2 to regulate human cardiomyocyte development
A mechanical-coupling mechanism in OSCA/TMEM63 channel mechanosensitivity
c-JUN is a barrier in hESC to cardiomyocyte transition
MYOCD is Required for Cardiomyocyte-like Cells Induction from Human Urine Cells and Fibroblasts Through Remodeling Chromatin
Why it is important to study human–monkey embryonic chimeras in a dish
Challenges and advances in clinical applications of mesenchymal stromal cells
The RNA m6A reader YTHDC1 silences retrotransposons and guards ES cell identity
Myeloid-derived suppressor cells promote lung cancer metastasis by CCL11 to activate ERK and AKT signaling and induce epithelial-mesenchymal transition in tumor cells
Cancer stem cells: advances in biology and clinical translation—a Keystone Symposia report
Glis1 facilitates induction of pluripotency via an epigenome–metabolome–epigenome signalling cascade
Treating COVID-19 with Chloroquine
Preliminary evidence from a multicenter prospective observational study of the safety and efficacy of chloroquine for the treatment of COVID-19
BMP4 resets mouse epiblast stem cells to naive pluripotency through ZBTB7A/B-mediated chromatin remodelling
Characterization and generation of human definitive multipotent hematopoietic stem/progenitor cells
Establishment of porcine and human expanded potential stem cells
Mesothelin is a target of chimeric antigen receptor T cells for treating gastric cancer
Mesenchymal–epithelial transition in development and reprogramming
Establishment of peripheral blood mononuclear cell-derived humanized lung cancer mouse models for studying efficacy of PD-L1/PD-1 targeted immunotherapy
Chemical reprogramming of mouse embryonic and adult fibroblast into endoderm lineage
Human Embryo Editing: Opportunities and Importance of Transnational Cooperation
CD215+ Myeloid Cells Respond to Interleukin 15 Stimulation and Promote Tumor Progression
Resolution of Reprogramming Transition States by Single Cell RNA-Sequencing
Hallmarks of pluripotency