Area of research
Molecular Biology · Oncology
Research interest
Research interests include CRISPR and Genetic Engineering, Melanoma and MAPK Pathways, RNA Interference and Gene Delivery, and RNA regulation and disease.
A path to translation: How 3D patient tumor avatars enable next generation precision oncology
A-MYB/TCFL5 regulatory architecture ensures the production of pachytene piRNAs in placental mammals
The transcription factor TCFL5 responds to A-MYB to elaborate the male meiotic program in mice
Dietary suppression of MHC class II expression in intestinal epithelial cells enhances intestinal tumorigenesis
Dietary suppression of MHC-II expression in intestinal stem cells enhances intestinal tumorigenesis
Evolutionarily conserved pachytene piRNA loci are highly divergent among modern humans
Cas9-mediated allelic exchange repairs compound heterozygous recessive mutations in mice
Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing
CRISPR/Cas9-mediated genome editing induces exon skipping by alternative splicing or exon deletion
Genetic disruption of oncogenic Kras sensitizes lung cancer cells to Fas receptor-mediated apoptosis
Genome-Wide CRISPR Screen Identifies Regulators of Mitogen-Activated Protein Kinase as Suppressors of Liver Tumors in Mice
Adenovirus-Mediated Somatic Genome Editing of <i>Pten</i> by CRISPR/Cas9 in Mouse Liver in Spite of Cas9-Specific Immune Responses
Interaction between AIF and CHCHD4 Regulates Respiratory Chain Biogenesis
Precision cancer mouse models through genome editing with CRISPR-Cas9
A versatile reporter system for CRISPR-mediated chromosomal rearrangements
A non-secretory form of FAM3B promotes invasion and metastasis of human colon cancer cells by upregulating Slug expression