Area of research
Oncology · Immunology
Research interest
Research interests include CAR-T cell therapy research, Monoclonal and Polyclonal Antibodies Research, Immune Cell Function and Interaction, and Immunotherapy and Immune Responses.
In vivo CRISPR screens identify modifiers of CAR T cell function in myeloma
On-target off-tumor toxicity of claudin18.2-directed CAR-T cells in preclinical models
Comparative analysis of Bcl-2 family protein overexpression in CAR T cells alone and in combination with BH3 mimetics
Chemical genetic control of cytokine signaling in CAR-T cells using lenalidomide-controlled membrane-bound degradable IL-7
CAR T cell killing requires the IFNγR pathway in solid but not liquid tumours
Reversible ON- and OFF-switch chimeric antigen receptors controlled by lenalidomide
CAR-T cells secreting BiTEs circumvent antigen escape without detectable toxicity
CRISPR-Cas9 disruption of PD-1 enhances activity of universal EGFRvIII CAR T cells in a preclinical model of human glioblastoma
Anti-CD37 chimeric antigen receptor T cells are active against B- and T-cell lymphomas