Area of research
Cancer Research · Oncology
Research interest
Research interests include Cancer Genomics and Diagnostics, CAR-T cell therapy research, Multiple Myeloma Research and Treatments, and Monoclonal and Polyclonal Antibodies Research.
SWIFT-seq enables comprehensive single-cell transcriptomic profiling of circulating tumor cells in multiple myeloma and its precursors
On-target off-tumor toxicity of claudin18.2-directed CAR-T cells in preclinical models
Comparative analysis of Bcl-2 family protein overexpression in CAR T cells alone and in combination with BH3 mimetics
Pan-cancer analysis of post-translational modifications reveals shared patterns of protein regulation
Author Correction: Analyses of non-coding somatic drivers in 2,658 cancer whole genomes
Author Correction: The repertoire of mutational signatures in human cancer
CAR T cell killing requires the IFNγR pathway in solid but not liquid tumours
Distinct cellular dynamics associated with response to CAR-T therapy for refractory B cell lymphoma
Designing sensitive viral diagnostics with machine learning
Single cell characterization of myeloma and its precursor conditions reveals transcriptional signatures of early tumorigenesis
Immune biomarkers of response to immunotherapy in patients with high-risk smoldering myeloma
Author Correction: Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis
Author Correction: Pathway and network analysis of more than 2500 whole cancer genomes
Author Correction: Integrative pathway enrichment analysis of multivariate omics data
The repertoire of mutational signatures in human cancer
Single-cell RNA sequencing reveals compromised immune microenvironment in precursor stages of multiple myeloma
Integrative pathway enrichment analysis of multivariate omics data
Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis
Pathway and network analysis of more than 2500 whole cancer genomes
DNA Polymerase and Mismatch Repair Exert Distinct Microsatellite Instability Signatures in Normal and Malignant Human Cells
Combined burden and functional impact tests for cancer driver discovery using DriverPower
A post-transcriptional program of chemoresistance by AU-rich elements and TTP in quiescent leukemic cells
Designing viral diagnostics with model-based optimization
RNA sequence analysis reveals macroscopic somatic clonal expansion across normal tissues
Scaling computational genomics to millions of individuals with GPUs
Structural Alterations Driving Castration-Resistant Prostate Cancer Revealed by Linked-Read Genome Sequencing
Quantification of somatic mutation flow across individual cell division events by lineage sequencing
Analysis of somatic microsatellite indels identifies driver events in human tumors
Discovery and characterization of coding and non-coding driver mutations in more than 2,500 whole cancer genomes
Mutational Strand Asymmetries in Cancer Genomes Reveal Mechanisms of DNA Damage and Repair