Area of research
Pulmonary and Respiratory Medicine · Oncology
Research interest
Research interests include Prostate Cancer Treatment and Research, Cancer Immunotherapy and Biomarkers, Protein Degradation and Inhibitors, and Pancreatic and Hepatic Oncology Research.
PROX1 is an early driver of lineage plasticity in prostate cancer
Stromal KITL/SCF Maintains Pancreas Tissue Homeostasis and Restrains Tumor Progression
Androgen Receptor Inhibition Increases MHC Class I Expression and Improves Immune Response in Prostate Cancer
LSD1 promotes prostate cancer reprogramming by repressing TP53 signaling independently of its demethylase function
Androgen receptor activity in T cells limits checkpoint blockade efficacy
Transcriptional profiling of matched patient biopsies clarifies molecular determinants of enzalutamide-induced lineage plasticity
A Cancer Cell–Intrinsic GOT2–PPARδ Axis Suppresses Antitumor Immunity
Identifying phenotype-associated subpopulations by integrating bulk and single-cell sequencing data
Transcriptional profiling identifies an androgen receptor activity-low, stemness program associated with enzalutamide resistance
Genomic Drivers of Poor Prognosis and Enzalutamide Resistance in Metastatic Castration-resistant Prostate Cancer
MEK-ERK signaling is a therapeutic target in metastatic castration resistant prostate cancer
Nudt21 regulates the alternative polyadenylation of Pak1 and is predictive in the prognosis of glioblastoma patients
Highly scalable generation of DNA methylation profiles in single cells
3′ UTR shortening represses tumor-suppressor genes in trans by disrupting ceRNA crosstalk
Human mutations in integrator complex subunits link transcriptome integrity to brain development
Gleason Score 7 Prostate Cancers Emerge through Branched Evolution of Clonal Gleason Pattern 3 and 4
Broad H3K4me3 is associated with increased transcription elongation and enhancer activity at tumor-suppressor genes
The Overlooked Fact: Fundamental Need for Spike-In Control for Virtually All Genome-Wide Analyses
PRMT9 is a Type II methyltransferase that methylates the splicing factor SAP145
Long Non-Coding RNAs Control Hematopoietic Stem Cell Function
Epigenomic Profiling of Young and Aged HSCs Reveals Concerted Changes during Aging that Reinforce Self-Renewal
Dynamic analyses of alternative polyadenylation from RNA-seq reveal a 3′-UTR landscape across seven tumour types
CFIm25 links alternative polyadenylation to glioblastoma tumour suppression
ZMYND11 links histone H3.3K36me3 to transcription elongation and tumour suppression
Dnmt3a and Dnmt3b Have Overlapping and Distinct Functions in Hematopoietic Stem Cells
The Histone-H3K4-Specific Demethylase KDM5B Binds to Its Substrate and Product through Distinct PHD Fingers
Rbfox2-Coordinated Alternative Splicing of Mef2d and Rock2 Controls Myoblast Fusion during Myogenesis
Whole Transcriptome Sequencing Reveals Extensive Unspliced mRNA in Metastatic Castration-Resistant Prostate Cancer