Area of research
Molecular Biology · Cognitive Neuroscience
Research interest
Research interests include Epigenetics and DNA Methylation, Genomics and Chromatin Dynamics, RNA modifications and cancer, and Cancer-related gene regulation.
Turn the Rudder: A Beacon of Reentrancy Detection for Smart Contracts on Ethereum
Multi-omic characterization of genome-wide abnormal DNA methylation reveals diagnostic and prognostic markers for esophageal squamous-cell carcinoma
3′ UTR shortening represses tumor-suppressor genes in trans by disrupting ceRNA crosstalk
DNMT3A and TET1 cooperate to regulate promoter epigenetic landscapes in mouse embryonic stem cells
Homeobox oncogene activation by pan-cancer DNA hypermethylation
Recurrence-Associated Long Non-coding RNA Signature for Determining the Risk of Recurrence in Patients with Colon Cancer
Analysis of long noncoding RNAs highlights region-specific altered expression patterns and diagnostic roles in Alzheimer’s disease
Targeted DNA methylation in vivo using an engineered dCas9-MQ1 fusion protein
DNA epigenome editing using CRISPR-Cas SunTag-directed DNMT3A
Transgenerational analysis of H3K4me3 and H3K27me3 by ChIP-Seq links epigenetic inheritance to metabolism
DNMT3A and TET2 compete and cooperate to repress lineage-specific transcription factors in hematopoietic stem cells
The identification of age-associated cancer markers by an integrative analysis of dynamic DNA methylation changes
Broad H3K4me3 is associated with increased transcription elongation and enhancer activity at tumor-suppressor genes
SEA: a super-enhancer archive
Systematic identification and annotation of human methylation marks based on bisulfite sequencing methylomes reveals distinct roles of cell type-specific hypomethylation in the regulation of cell identity genes
The Identification of Specific Methylation Patterns across Different Cancers
Chromatin modifications and genomic contexts linked to dynamic DNA methylation patterns across human cell types
DNA Methylation Patterns Can Estimate Nonequivalent Outcomes of Breast Cancer with the Same Receptor Subtypes
CellMethy: Identification of a focal concordantly methylated pattern of CpGs revealed wide differences between normal and cancer tissues
MetaImprint: an information repository of mammalian imprinted genes
Detection of type 2 diabetes related modules and genes based on epigenetic networks
Long non-coding RNA identification over mouse brain development by integrative modeling of chromatin and genomic features
Quantitative epigenetic co-variation in CpG islands and co-regulation of developmental genes
Revealing the architecture of genetic and epigenetic regulation: a maximum likelihood model
Genome-wide identification of Polycomb target genes in human embryonic stem cells
CpG_MPs: identification of CpG methylation patterns of genomic regions from high-throughput bisulfite sequencing data