Area of research
Molecular Biology · Nephrology
Research interest
Research interests include Epigenetics and DNA Methylation, Renal and related cancers, Chronic Kidney Disease and Diabetes, and CRISPR and Genetic Engineering.
Kidney multiome-based genetic scorecard reveals convergent coding and regulatory variants
252 Inconsistency of HER2 Status Between Core Needle Biopsy and Surgical Specimens: Focus on HER2 Null, HER2 Ultralow, and HER2 Low
Combined transcriptome and metabolome analysis reveals the mechanism of high nitrite tolerance in freshwater mussel Anodonta woodiana
DNA methylation markers for kidney function and progression of diabetic kidney disease
Unbiased Human Kidney Tissue Proteomics Identifies Matrix Metalloproteinase 7 as a Kidney Disease Biomarker
ACSS2 gene variants determine kidney disease risk by controlling de novo lipogenesis in kidney tubules
Transcriptome- and proteome-wide association studies nominate determinants of kidney function and damage
Exploring a novel therapeutic strategy: the interplay between gut microbiota and high-fat diet in the pathogenesis of metabolic disorders
Epigenomic and transcriptomic analyses define core cell types, genes and targetable mechanisms for kidney disease (Data Set)
Genome-wide meta-analysis and omics integration identifies novel genes associated with diabetic kidney disease
Epigenomic and transcriptomic analyses define core cell types, genes and targetable mechanisms for kidney disease (Data Set)
Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments
Meta-analyses identify DNA methylation associated with kidney function and damage
Renal Histologic Analysis Provides Complementary Information to Kidney Function Measurement for Patients with Early Diabetic or Hypertensive Disease
Epigenome-wide association study of serum urate reveals insights into urate co-regulation and the SLC2A9 locus
Mitochondrial DNA and microsatellite analyses reveal strong genetic differentiation between two types of estuarine tapertail anchovies (Coilia) in Yangtze River Basin, China
Systematic integrated analysis of genetic and epigenetic variation in diabetic kidney disease
Glycogen synthase kinase-3β: a promising candidate in the fight against fibrosis
Genome and population sequencing of a chromosome-level genome assembly of the Chinese tapertail anchovy (<i>Coilia nasus</i>) provides novel insights into migratory adaptation
Specific breast cancer prognosis‐subtype distinctions based on<scp>DNA</scp>methylation patterns
Disruption of the ZBED6 binding site in intron 3 of IGF2 by CRISPR/Cas9 leads to enhanced muscle development in Liang Guang Small Spotted pigs
Survival differences of CIMP subtypes integrated with CNA information in human breast cancer
DiseaseMeth version 2.0: a major expansion and update of the human disease methylation database
The identification of age-associated cancer markers by an integrative analysis of dynamic DNA methylation changes
DNA methylation dynamics: identification and functional annotation
DNA methylation, the charm of dynamics
Systematic identification and annotation of human methylation marks based on bisulfite sequencing methylomes reveals distinct roles of cell type-specific hypomethylation in the regulation of cell identity genes
The Identification of Specific Methylation Patterns across Different Cancers
Folic Acid Alters Methylation Profile of JAK-STAT and Long-Term Depression Signaling Pathways in Alzheimer’s Disease Models
Chromatin modifications and genomic contexts linked to dynamic DNA methylation patterns across human cell types