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Yan Zhang

Texas A&M University System · US
Area of research
Cancer Research · Molecular Biology
Research interest
Research interests include Cancer-related molecular mechanisms research, MicroRNA in disease regulation, Circular RNAs in diseases, and RNA modifications and cancer.
h-index
52
citations
10,085
works
428
NIH funding
primary concept
email

Recent publications

RUNX2 Phase Separation Mediates Long-Range Regulation Between Osteoporosis-Susceptibility Variant and XCR1 to Promote Osteoblast Differentiation.
2025cited by 5position: contributordoi
Deficiency of Cbfβ in articular cartilage leads to osteoarthritis-like phenotype through Hippo/Yap, TGFβ, and Wnt/β-catenin signaling pathways
International Journal of Biological Sciences 2024cited by 12position: firstdoi
Cbfβ regulates Wnt/β-catenin, Hippo/Yap, and Tgfβ signaling pathways in articular cartilage homeostasis and protects from ACLT surgery-induced osteoarthritis
eLife 2024cited by 12position: middledoi
Deficiency of Cbfβ in articular cartilage leads to osteoarthritis-like phenotype through Hippo/Yap, TGFβ, and Wnt/β-catenin signaling pathways.
2024cited by 12position: contributordoi
Isolation and culture of human primary osteoblasts: Comparing the effects of differences in method details on osteoblast characteristics.
2024cited by 4position: contributordoi
Mosquitocidal toxin-like islands in Bacillus thuringiensis S2160-1 revealed by complete-genome sequence and MS proteomic analysis
Scientific Reports 2024cited by 3position: middledoi
Dysregulated transfer RNA-derived small RNAs as potential gastric cancer biomarkers
Experimental Biology and Medicine 2024cited by 2position: middledoi
Enhancer variants on chromosome 2p14 regulating SPRED2 and ACTR2 act as a signal amplifier to protect against rheumatoid arthritis.
2023cited by 6position: contributordoi
Long non-coding RNA <i>NRAV</i> in the 12q24.31 risk locus drives gastric cancer development through glucose metabolism reprogramming
Carcinogenesis 2023cited by 5position: firstdoi
Runx1 is a key regulator of articular cartilage homeostasis by orchestrating YAP, TGFβ, and Wnt signaling in articular cartilage formation and osteoarthritis
Bone Research 2022cited by 48position: firstdoi
Runx1 is a key regulator of articular cartilage homeostasis by orchestrating YAP, TGFβ, and Wnt signaling in articular cartilage formation and osteoarthritis.
2022cited by 38position: contributordoi
MiR-138-5p Targets MACF1 to Aggravate Aging-related Bone Loss.
2022cited by 33position: contributordoi
GPR125 positively regulates osteoclastogenesis potentially through AKT-NF-κB and MAPK signaling pathways
International Journal of Biological Sciences 2022cited by 30position: middledoi
Exosome-Derived microRNA: Implications in Melanoma Progression, Diagnosis and Treatment
Cancers 2022cited by 30position: middledoi
WDR72 regulates vesicle trafficking in ameloblasts
Scientific Reports 2022cited by 26position: middledoi
Total flavonoids of Rhizoma Drynariae enhances CD31<sup>hi</sup>Emcn<sup>hi</sup> vessel formation and subsequent bone regeneration in rat models of distraction osteogenesis by activating PDGF‑BB/VEGF/RUNX2/OSX signaling axis
International Journal of Molecular Medicine 2022cited by 20position: middledoi
GPR125 positively regulates osteoclastogenesis potentially through AKT-NF-κB and MAPK signaling pathways.
2022cited by 18position: contributordoi
Long noncoding RNA Lnc-DIF inhibits bone formation by sequestering miR-489-3p.
2022cited by 10position: contributordoi
Extracellular vesicle drug occupancy enables real-time monitoring of targeted cancer therapy
Nature Nanotechnology 2021cited by 105position: middledoi
Role of Exosomal MicroRNAs and Their Crosstalk with Oxidative Stress in the Pathogenesis of Osteoporosis
Oxidative Medicine and Cellular Longevity 2021cited by 22position: middledoi
MACF1 alleviates aging-related osteoporosis via HES1.
2021cited by 14position: contributordoi
Precision treatment exploration of breast cancer based on heterogeneity analysis of lncRNAs at the single-cell level
BMC Cancer 2021cited by 9position: firstdoi
New insights for precision treatment of glioblastoma from analysis of single-cell lncRNA expression
Journal of Cancer Research and Clinical Oncology 2021cited by 6position: middledoi
Runx1 up-regulates chondrocyte to osteoblast lineage commitment and promotes bone formation by enhancing both chondrogenesis and osteogenesis
Biochemical Journal 2020cited by 74position: middledoi
Runx1 up-regulates chondrocyte to osteoblast lineage commitment and promotes bone formation by enhancing both chondrogenesis and osteogenesis.
2020cited by 54position: contributordoi
Recombinant Irisin Prevents the Reduction of Osteoblast Differentiation Induced by Stimulated Microgravity through Increasing β-Catenin Expression.
2020cited by 43position: contributordoi
LncRNA HOTAIR Participates in Microglia Activation and Inflammatory Factor Release by Regulating the Ubiquitination of MYD88 in Traumatic Brain Injury
Journal of Molecular Neuroscience 2020cited by 42position: middledoi
Silencing of miR-138-5p sensitizes bone anabolic action to mechanical stimuli.
2020cited by 37position: contributordoi
The Application of MSCs-Derived Extracellular Vesicles in Bone Disorders: Novel Cell-Free Therapeutic Strategy.
2020cited by 34position: contributordoi
Mesenchymal MACF1 Facilitates SMAD7 Nuclear Translocation to Drive Bone Formation
Cells 2020cited by 33position: middledoi

Grants

CAREER: Expanding and Leveraging the Natural Diversity of Type I CRISPR for Genome Engineering
NSF2338912$700,0102024–2029PIRePORTER
Understanding Pulsatile Helical Flow: Scaling, Turbulence, and Helicity Control
NSF2342517$304,8422024–2026PIRePORTER
Equipment: MRI: Track 1 Acquisition of A Research Ultrasound System for Multidisciplinary Flow and Fluid-Structure Interaction Studies
NSF2407388$236,1932024–2027PIRePORTER
Switched Capacitor Wavelet Filter for VLSI Implementation
NSF9260651$49,8171993–1993PIRePORTER

Frequent collaborators

Maoni Guo · Harbin Medical University6 papers (2016–2020)Jie Lv · Zhengzhou University6 papers (2013–2014)Peng Wang · Fudan University6 papers (2016–2020)Shangwei Ning · Harbin Medical University6 papers (2016–2020)Hui Zhi · Harbin Medical University6 papers (2016–2020)Ali Ahmed · University of Kordofan6 papers (2012–2014)Qiong Wu · University of Iowa5 papers (2013–2016)Yue Gao · National University of Singapore5 papers (2016–2020)Thomas E. Love · Georgetown University5 papers (2012–2013)Inmaculada Aban · University of Alabama at Birmingham5 papers (2012–2013)Ming Yue · Ocean University of China5 papers (2016–2020)Abigail McVicar · University of Alabama at Birmingham5 papers (2020–2024)Hongbo Liu · Yanbian University5 papers (2013–2014)Gregg C. Fonarow · UCLA Medical Center5 papers (2012–2013)Hui Liu · Central South University of Forestry and Technology5 papers (2013–2016)Xia Li · Beijing Shijitan Hospital5 papers (2016–2018)Jing Guo · Betta Pharmaceuticals (China)4 papers (2013–2016)Hongjuan He · Ministry of Education of the People's Republic of China4 papers (2013–2016)Jizhou Zhang · Nanjing University of Chinese Medicine4 papers (2016–2020)Kanan Patel · University of California, San Francisco4 papers (2012–2013)