Area of research
Physiology · Neurology
Research interest
Research interests include Biology, Cell biology, Neuroscience, ADAM10, Receptor, and Pathogenesis.
Multicenter Longitudinal Quality Assessment of MS-Based Proteomics in Plasma and Serum
Multicenter evaluation of label-free quantification in human plasma on a high dynamic range benchmark set
A unified classification approach rating clinical utility of protein biomarkers across neurologic diseases
Deciphering sources of PET signals in the tumor microenvironment of glioblastoma at cellular resolution
Deciphering sources of PET signals in the tumor microenvironment of glioblastoma at cellular resolution
ADAM10 and ADAM17 promote SARS‐CoV‐2 cell entry and spike protein‐mediated lung cell fusion
Experimental evidence for temporal uncoupling of brain Aβ deposition and neurodegenerative sequelae
Signatures of glial activity can be detected in the CSF proteome
Proteolytically generated soluble Tweak Receptor Fn14 is a blood biomarker for γ‐secretase activity
The case for low-level BACE1 inhibition for the prevention of Alzheimer disease
Highly efficient intercellular spreading of protein misfolding mediated by viral ligand-receptor interactions
Shed CNTNAP2 ectodomain is detectable in CSF and regulates Ca2+ homeostasis and network synchrony via PMCA2/ATP2B2
Fibroblast Growth Factor 2‐Mediated Regulation of Neuronal Exosome Release Depends on VAMP3/Cellubrevin in Hippocampal Neurons
Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity
Degradome of soluble ADAM10 and ADAM17 metalloproteases
NrCAM is a marker for substrate‐selective activation of ADAM10 in Alzheimer's disease
BACE2 distribution in major brain cell types and identification of novel substrates
BACE1 Physiological Functions May Limit Its Use as Therapeutic Target for Alzheimer's Disease
Seizure protein 6 and its homolog seizure 6-like protein are physiological substrates of BACE1 in neurons
Generation of aggregation prone N-terminally truncated amyloid β peptides by meprin β depends on the sequence specificity at the cleavage site
Function, therapeutic potential and cell biology of <scp>BACE</scp> proteases: current status and future prospects
Dietary (−)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing
The FTLD risk factor TMEM106B and MAP6 control dendritic trafficking of lysosomes
Chronic 5-HT4 receptor activation decreases Aβ production and deposition in hAPP/PS1 mice
Computational identification and experimental validation of microRNAs binding to the Alzheimer-related gene ADAM10
Loss of PAFAH1B2 Reduces Amyloid-β Generation by Promoting the Degradation of Amyloid Precursor Protein C-Terminal Fragments