Zizhang Sheng

Env-antibody coevolution identifies B cell priming as the principal bottleneck to HIV V2 apex broadly neutralizing antibody development.

NanoHIVSeq: A Long-Read Bioinformatics Pipeline for High-Throughput Processing of HIV Env Sequences

Structural and genetic basis of HIV-1 envelope V2 apex recognition by rhesus broadly neutralizing antibodies

Env-antibody coevolution identifies B cell priming as the principal bottleneck to HIV-1 V2 apex broadly neutralizing antibody development

Structural and genetic basis of HIV-1 envelope V2 apex recognition by rhesus broadly neutralizing antibodies.

Single-cell and clonal analysis of AL amyloidosis plasma cells and their bone marrow microenvironment.

Genetic Diversity of the Malaria Vaccine Candidate PfRIPR in a High Transmission Region of Senegal

Yeast Display Reveals Plentiful Mutations That Improve Fusion Peptide Vaccine-Elicited Antibodies Beyond 59% HIV-1 Neutralization Breadth.

Distinct CD8 ⁺ T-cell types Associated with COVID-19 Severity in Unvaccinated HLA-A2 ⁺ Patients

Potent and broad HIV-1 neutralization in fusion peptide-primed SHIV-infected macaques

HIV-1 neutralizing antibodies in SHIV-infected macaques recapitulate structurally divergent modes of human V2 apex recognition with a single D gene

Genetic diversity in the Plasmodium falciparum next-generation blood stage vaccine candidate antigen PfCyRPA in Senegal

Vaccine-induced human monoclonal antibodies to PfRH5 show broadly neutralizing activity against <i>P. falciparum</i> clinical isolates

Structures of LRP2 reveal a molecular machine for endocytosis

Antibodies targeting a quaternary site on SARS-CoV-2 spike glycoprotein prevent viral receptor engagement by conformational locking

<scp>Single‐Cell</scp> Profiling of Bone Marrow B Cells and Early B Cell Developmental Disorders Associated With Systemic Lupus Erythematosus

Antibodies that neutralize all current SARS-CoV-2 variants of concern by conformational locking

Evolving antibody evasion and receptor affinity of the Omicron BA.2.75 sublineage of SARS-CoV-2

Alarming antibody evasion properties of rising SARS-CoV-2 BQ and XBB subvariants

Antibody Evasion Properties of SARS-CoV-2 Omicron Sublineages

An antibody class with a common CDRH3 motif broadly neutralizes sarbecoviruses.

Alarming antibody evasion properties of rising SARS-CoV-2 BQ and XBB subvariants

Multiple pathways for SARS-CoV-2 resistance to nirmatrelvir

Antigenic characterization of the SARS-CoV-2 Omicron subvariant BA.2.75

Antibody evasion by SARS-CoV-2 Omicron subvariants BA.2.12.1, BA.4, and BA.5

SARS-CoV-2 Omicron BA.2.12.1, BA.4, and BA.5 subvariants evolved to extend antibody evasion

Resistance of SARS-CoV-2 Omicron Subvariant BA.4.6 to Antibody Neutralization

Identification of novel genetic variants in the malaria vaccine candidate PfRh5: structure-guided insights into potential function

Increased Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 to Antibody Neutralization

Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7