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Neil L. Kelleher

Northwestern University · US
🔎 Find collaborators in Spectroscopy · Molecular Biology →
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Area of research
Spectroscopy · Molecular Biology
Research interest
Research interests include Advanced Proteomics Techniques and Applications, Mass Spectrometry Techniques and Applications, Microbial Natural Products and Biosynthesis, and Metabolomics and Mass Spectrometry Studies.
h-index
107
citations
45,159
works
716
NIH funding
primary concept
Chemistry
email

Recent publications

Short-chain fatty acid metabolites propionate and butyrate are unique epigenetic regulatory elements linking diet, metabolism and gene expression
Nature Metabolism 2025cited by 104position: middledoi
Human BioMolecular Atlas Program (HuBMAP): 3D Human Reference Atlas construction and usage
Nature Methods 2025cited by 26position: middledoi
A needed nomenclature for nucleosomes
Molecular Cell 2025cited by 9position: middledoi
Blocking C-terminal processing of KRAS4b via a direct covalent attack on the CaaX-box cysteine
Proceedings of the National Academy of Sciences 2025cited by 5position: middledoi
Intact Proteoform Analysis by Capillary Electrophoresis–Mass Spectrometry. Are We There Yet?
Angewandte Chemie International Edition 2025cited by 4position: middledoi
π-HuB: the proteomic navigator of the human body
Nature 2024cited by 40position: middledoi
Top-down mass spectrometry of native proteoforms and their complexes: a community study
Nature Methods 2024cited by 37position: middledoi
Bioactivity-driven fungal metabologenomics identifies antiproliferative stemphone analogs and their biosynthetic gene cluster
Metabolomics 2024cited by 8position: middledoi
Advances and prospects for the Human BioMolecular Atlas Program (HuBMAP)
Nature Cell Biology 2023cited by 168position: middledoi
Organ Mapping Antibody Panels: a community resource for standardized multiplexed tissue imaging
Nature Methods 2023cited by 44position: middledoi
The Blood Proteoform Atlas: A reference map of proteoforms in human hematopoietic cells
Science 2022cited by 144position: lastdoi
New Views of Old Proteins: Clarifying the Enigmatic Proteome
Molecular & Cellular Proteomics 2022cited by 35position: lastdoi
The emerging landscape of single-molecule protein sequencing technologies
Nature Methods 2021cited by 357position: middledoi
The Human Proteoform Project: Defining the human proteome
Science Advances 2021cited by 239position: lastdoi
A community resource for paired genomic and metabolomic data mining
Nature Chemical Biology 2021cited by 129position: middledoi
Spatial mapping of protein composition and tissue organization: a primer for multiplexed antibody-based imaging
Nature Methods 2021cited by 22position: middledoi
Histone H1 loss drives lymphoma by disrupting 3D chromatin architecture
Nature 2020cited by 263position: middledoi
Mutant EZH2 Induces a Pre-malignant Lymphoma Niche by Reprogramming the Immune Response
Cancer Cell 2020cited by 157position: middledoi
Interlaboratory Study for Characterizing Monoclonal Antibodies by Top-Down and Middle-Down Mass Spectrometry
Journal of the American Society for Mass Spectrometry 2020cited by 126position: middledoi
NMT1 and NMT2 are lysine myristoyltransferases regulating the ARF6 GTPase cycle
Nature Communications 2020cited by 105position: middledoi
The serine hydroxymethyltransferase-2 (SHMT2) initiates lymphoma development through epigenetic tumor suppressor silencing
Nature Cancer 2020cited by 69position: middledoi
Histone tail analysis reveals H3K36me2 and H4K16ac as epigenetic signatures of diffuse intrinsic pontine glioma
Journal of Experimental & Clinical Cancer Research 2020cited by 37position: middledoi
A computational framework to explore large-scale biosynthetic diversity
Nature Chemical Biology 2019cited by 1,030position: middledoi
Best practices and benchmarks for intact protein analysis for top-down mass spectrometry
Nature Methods 2019cited by 386position: middledoi
A Mutation in Histone H2B Represents a New Class of Oncogenic Driver
Cancer Discovery 2019cited by 104position: middledoi
A five-level classification system for proteoform identifications
Nature Methods 2019cited by 98position: lastdoi
Multidimensional Top-Down Proteomics of Brain-Region-Specific Mouse Brain Proteoforms Responsive to Cocaine and Estradiol
Journal of Proteome Research 2019cited by 16position: middledoi
How many human proteoforms are there?
Nature Chemical Biology 2018cited by 934position: middledoi
USP7 Cooperates with NOTCH1 to Drive the Oncogenic Transcriptional Program in T-Cell Leukemia
Clinical Cancer Research 2018cited by 92position: middledoi
A Targeted, Differential Top-Down Proteomic Methodology for Comparison of ApoA-I Proteoforms in Individuals with High and Low HDL Efflux Capacity
Journal of Proteome Research 2018cited by 40position: middledoi

Grants

CAREER: Research and Education to Further Knowledge and Literacy in the Postgenomic Sciences
NSF0134953$540,0002002–2006PIRePORTER

Frequent collaborators

Paul M. Thomas · Northwestern University8 papers (2014–2020) · 8 papers (2014–2019)Yupeng Zheng · Beijing Tongren Hospital6 papers (2013–2017)Richard D. LeDuc · University of Manitoba6 papers (2014–2019)Luca Fornelli · University of Oklahoma4 papers (2016–2018)Jeffrey N. Agar · Northeastern University4 papers (2014–2024)Ljiljana Paša‐Tolić · Environmental Molecular Sciences Laboratory4 papers (2014–2024)Jeannie M. Camarillo · Northwestern University4 papers (2020–2025) · 3 papers (2016–2019) · 3 papers (2014–2016)William W. Metcalf · University of Illinois Urbana-Champaign3 papers (2013–2019) · 3 papers (2019–2024)Lloyd M. Smith · University of Wisconsin–Madison3 papers (2013–2021)Kenneth R. Durbin · AbbVie (United States)3 papers (2012–2016)Jonathan D. Licht · Van Andel Institute3 papers (2013–2019)Lissa C. Anderson · University of Virginia3 papers (2016–2019)Emma Lundberg · Palo Alto University3 papers (2015–2022) · 3 papers (2014–2021)Philip D. Compton · University of Virginia3 papers (2015–2018)Caroline J. DeHart · Princeton University3 papers (2016–2020)
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