Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include Metabolomics and Mass Spectrometry Studies, Cancer, Hypoxia, and Metabolism, Immune cells in cancer, and Microbial Metabolic Engineering and Bioproduction.
NLRP3-mediated glutaminolysis controls microglial phagocytosis to promote Alzheimer’s disease progression
ACC1 is a dual metabolic-epigenetic regulator of Treg stability and immune tolerance
Metabolic reprogramming of interleukin-17-producing γδ T cells promotes ACC1-mediated de novo lipogenesis under psoriatic conditions
Oligodendroglial fatty acid metabolism as a central nervous system energy reserve
Impaired ketogenesis ties metabolism to T cell dysfunction in COVID-19
Mesaconate is synthesized from itaconate and exerts immunomodulatory effects in macrophages
The importance of biofilm formation for cultivation of a Micrarchaeon and its interactions with its Thermoplasmatales host
BCAT1 redox function maintains mitotic fidelity
Transcriptional licensing is required for Pyrin inflammasome activation in human macrophages and bypassed by mutations causing familial Mediterranean fever
Systemic Lactate Acts as a Metabolic Buffer in Humans and Prevents Nutrient Overflow in the Postprandial Phase
Plasma Metabolome Signature Indicative of BRCA1 Germline Status Independent of Cancer Incidence
Unraveling the critical growth factors for stable cultivation of (nano-sized) Micrarchaeota
Variations in microbiota composition of laboratory mice influence Citrobacter rodentium infection via variable short-chain fatty acid production
Oncogenic IDH1 Mutations Promote Enhanced Proline Synthesis through PYCR1 to Support the Maintenance of Mitochondrial Redox Homeostasis
Author Correction: BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation
Glutathione Primes T Cell Metabolism for Inflammation
BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation
Erythritol is a pentose-phosphate pathway metabolite and associated with adiposity gain in young adults
Branched‐chain ketoacids secreted by glioblastoma cells via MCT1 modulate macrophage phenotype
Immunoresponsive Gene 1 and Itaconate Inhibit Succinate Dehydrogenase to Modulate Intracellular Succinate Levels
Distinct Metabolic States Can Support Self-Renewal and Lipogenesis in Human Pluripotent Stem Cells under Different Culture Conditions
Dual loss of succinate dehydrogenase (SDH) and complex I activity is necessary to recapitulate the metabolic phenotype of SDH mutant tumors
Loss of DJ-1 impairs antioxidant response by altered glutamine and serine metabolism
A roadmap for interpreting 13C metabolite labeling patterns from cells
Itaconic Acid: The Surprising Role of an Industrial Compound as a Mammalian Antimicrobial Metabolite
Profiling metabolic networks to study cancer metabolism