Area of research
Molecular Biology · Physiology
Research interest
Research focused on Allosteric regulation and Heterotrimeric G protein, with related work in G protein-coupled receptor, Allosteric modulator, Adenosine receptor. Notable publications include 'Structure of the adenosine-bound human adenosine A1 receptor–Gi complex', 'Positive allosteric mechanisms of adenosine A1 receptor-mediated analgesia', and 'Dominant Negative G Proteins Enhance Formation and Purification of Agonist-GPCR-G Protein Complexes for Structure Determination'.
Positive allosteric mechanisms of adenosine A1 receptor-mediated analgesia
Structure of the adenosine-bound human adenosine A1 receptor–Gi complex
Dominant Negative G Proteins Enhance Formation and Purification of Agonist-GPCR-G Protein Complexes for Structure Determination
Structure-based discovery of selective positive allosteric modulators of antagonists for the M <sub>2</sub> muscarinic acetylcholine receptor