Area of research
Immunology · Rheumatology
Research interest
Research interests include T-cell and B-cell Immunology, Immune Cell Function and Interaction, Rheumatoid Arthritis Research and Therapies, and Systemic Lupus Erythematosus Research.
Granzyme K activates the entire complement cascade
Deep immunophenotyping reveals circulating activated lymphocytes in individuals at risk for rheumatoid arthritis
Synovial fibroblast gene expression is associated with sensory nerve growth and pain in rheumatoid arthritis
Tissue-specific enhancer–gene maps from multimodal single-cell data identify causal disease alleles
Clonal associations between lymphocyte subsets and functional states in rheumatoid arthritis synovium
The chromatin landscape of pathogenic transcriptional cell states in rheumatoid arthritis
Adipocyte associated glucocorticoid signaling regulates normal fibroblast function which is lost in inflammatory arthritis
Automated multi-scale computational pathotyping (AMSCP) of inflamed synovial tissue
Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes
Clonally expanded CD38 <sup>hi</sup> cytotoxic CD8 T cells define the T cell infiltrate in checkpoint inhibitor–associated arthritis
Mapping the dynamic genetic regulatory architecture of HLA genes at single-cell resolution
Granzyme K <sup>+</sup> CD8 T cells form a core population in inflamed human tissue
Cross-tissue, single-cell stromal atlas identifies shared pathological fibroblast phenotypes in four chronic inflammatory diseases
High incidence of proliferative and membranous nephritis in SLE patients with low proteinuria in the Accelerating Medicines Partnership
Persistence and Evolution of SARS-CoV-2 in an Immunocompromised Host
Notch signalling drives synovial fibroblast identity and arthritis pathology
Th17 reprogramming of T cells in systemic juvenile idiopathic arthritis
Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry
The immune cell landscape in kidneys of patients with lupus nephritis
2018 American College of Rheumatology/National Psoriasis Foundation Guideline for the Treatment of Psoriatic Arthritis
2018 American College of Rheumatology/National Psoriasis Foundation Guideline for the Treatment of Psoriatic Arthritis
2018 American College of Rheumatology/National Psoriasis Foundation Guideline for the Treatment of Psoriatic Arthritis
Natural killer cell licensing in mice with inducible expression of MHC class I
Inositol tetrakisphosphate limits NK cell effector functions by controlling PI3K signaling