Area of research
Pathology and Forensic Medicine · Neurology
Research interest
Alberto Ascherio, MD, DrPH, is a Professor of Epidemiology and Nutrition at the Harvard T. H. Chan School of Public Health and a Professor of Medicine at the Harvard Medical School. Dr. Ascherio received a Doctorate in Medicine and Surgery from the University of Milan and worked for several years in medicine and public health in Latin America and Africa before obtaining a Master and Doctorate in Public Health from Harvard. Dr. Ascherio has focused much of his work over the past 25 years on discovering the causes of neurodegenerative diseases, including multiple sclerosis (MS), Parkinson disease, amyotrophic lateral sclerosis, and cognitive decline. He has conducted longitudinal studies in many populations, including, among others, the Nurses’ Health Studies I and II, the Health Professionals Follow-up Study, the Cancer Prevention Study-II, the U.S Army, Navy and Air Force, the Danish MS Registry, and the Finnish Maternal Cohort. These studies have contributed to identifying several biomarkers and modifiable risk factors for MS (e.g. cigarette smoking, vitamin D insufficiency, and childhood obesity), Parkinson (pesticide exposure, low caffeine intake, low physical activity), and ALS (cigarette smoking, military service, low body mass index), and have in some cases provided the rationale for randomized trials (e.g. on physical activity in Parkinson disease). His most notable scientific contribution stems from the 20-year long investigation of over 10 million young adults that led to the recent breakthrough discovery that MS is a rare complication of infection with the Epstein-Barr virus.
Slow-SPEED: protocol for three randomised trials of remotely delivered exercise to prevent Parkinson’s disease
Long-Term Consumption of Ultraprocessed Foods and Prodromal Features of Parkinson Disease
Long-Term Consumption of Ultraprocessed Foods and Prodromal Features of Parkinson Disease.
Plasma Metabolomics Profiles in Prodromal and Clinical Parkinson's Disease.
Serum Alpha-Linolenic Acid and Long-Term Multiple Sclerosis Activity and Progression
Serologic Response to the Epstein-Barr Virus Peptidome and the Risk for Multiple Sclerosis
Epstein-Barr virus as a leading cause of multiple sclerosis: mechanisms and implications.
Association of the Mediterranean Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) Diet With the Risk of Dementia
Integrating genetics and metabolomics from multi-ethnic and multi-fluid data reveals putative mechanisms for age-related macular degeneration
Long‐Term Intake of Folate, Vitamin <scp>B6</scp>, and Vitamin <scp>B12</scp> and the Incidence of Parkinson's Disease in a Sample of <scp>U.S.</scp> Women and Men
The intricate connection between diabetes mellitus and Parkinson's disease.
Longitudinal analysis reveals high prevalence of Epstein-Barr virus associated with multiple sclerosis
Longitudinal analysis reveals high prevalence of Epstein-Barr virus associated with multiple sclerosis.
The Potential for EBV Vaccines to Prevent Multiple Sclerosis
Association of Diet and Physical Activity With All-Cause Mortality Among Adults With Parkinson Disease
Early Diagnosis of Multiple Sclerosis: Further Evidence for Missed Opportunity.
Maternal prepregnancy BMI and physical activity and type 1 diabetes in the offspring.
The Mediterranean diet, plasma metabolome, and cardiovascular disease risk
Serum Neurofilament Light Chain Levels in Patients With Presymptomatic Multiple Sclerosis
Sex differences by design and outcome in the Safety of Urate Elevation in PD (SURE-PD) trial
Epidemiology of Multiple Sclerosis: From Risk Factors to Prevention—An Update
Association of Vitamin D Levels With Multiple Sclerosis Activity and Progression in Patients Receiving Interferon Beta-1b
Gout and the risk of Alzheimer's disease: a population-based, BMI-matched cohort study
Vitamin D as an Early Predictor of Multiple Sclerosis Activity and Progression
Inosine to Increase Serum and Cerebrospinal Fluid Urate in Parkinson Disease
Mendelian randomization of serum urate and parkinson disease progression
Environmental factors in multiple sclerosis
Research on the Premotor Symptoms of Parkinson’s Disease: Clinical and Etiological Implications
Habitual intake of dietary flavonoids and risk of Parkinson disease
The initiation and prevention of multiple sclerosis