Area of research
Cardiology and Cardiovascular Medicine · Molecular Biology
Research interest
Research interests include Cardiomyopathy and Myosin Studies, Muscle Physiology and Disorders, Cardiovascular Function and Risk Factors, and MicroRNA in disease regulation.
Enhancer AAV toolbox for accessing and perturbing striatal cell types and circuits
Interneuron-specific dual-AAV <i>SCN1A</i> gene replacement corrects epileptic phenotypes in mouse models of Dravet syndrome
AAV delivery of full-length SYNGAP1 rescues epileptic and behavioral phenotypes in a mouse model of SYNGAP1-related disorders
Enhancer-AAVs allow genetic access to oligodendrocytes and diverse populations of astrocytes across species
Enhancer-AAVs allow genetic access to oligodendrocytes and diverse populations of astrocytes across species
A versatile cell line for establishing potency of cell type-specific AAV transgenes
Adeno-associated viral vectors for functional intravenous gene transfer throughout the non-human primate brain
Enhancer-AAVs allow genetic access to oligodendrocytes and diverse populations of astrocytes across species
AAV-mediated interneuron-specific gene replacement for Dravet syndrome
Functional enhancer elements drive subclass-selective expression from mouse to primate neocortex
Mavacamten decreases maximal force and Ca<sup>2+</sup> sensitivity in the N47K-myosin regulatory light chain mouse model of hypertrophic cardiomyopathy
Functional Enhancer Elements Drive Subclass-Selective Expression from Mouse to Primate Neocortex
Functional enhancer elements drive subclass-selective expression from mouse to primate neocortex