Area of research
Neurology · Genetics
Research interest
Research focused on LRRK2 and Parkinson's disease, with related work in Disease, Genetics, Cell biology. Notable publications include 'Clinical profiles of Parkinson's disease associated with common leucine-rich repeat kinase 2 and glucocerebrosidase genetic variants in Chinese individuals', 'Penetrance of LRRK2 G2385R and R1628P is modified by common PD-associated genetic variants', and 'Genome-wide association study using whole-genome sequencing identifies risk loci for Parkinson’s disease in Chinese population'.
Clinical and genetic characteristics of late-onset cobalamin C deficiency: A multicenter study in northern China
Heterogeneous blood‐brain barrier dysfunction in cerebral small vessel diseases
Genome-wide association study using whole-genome sequencing identifies risk loci for Parkinson’s disease in Chinese population
Decreased water exchange rate across blood–brain barrier in hereditary cerebral small vessel disease
Clinical profiles of Parkinson's disease associated with common leucine-rich repeat kinase 2 and glucocerebrosidase genetic variants in Chinese individuals
IRGM1 regulates oxidized LDL uptake by macrophage via actin-dependent receptor internalization during atherosclerosis
Penetrance of LRRK2 G2385R and R1628P is modified by common PD-associated genetic variants
Immune-related GTPase M (IRGM1) regulates neuronal autophagy in a mouse model of stroke
Immune-related GTPase Irgm1 exacerbates experimental auto-immune encephalomyelitis by promoting the disruption of blood–brain barrier and blood–cerebrospinal fluid barrier