Area of research
Cancer Research · Genetics
Research interest
Research focused on Neuroinflammation and Autophagy, with related work in Macrophage, Neuroprotection, Cell biology. Notable publications include 'Expansion of Human-Specific GGC Repeat in Neuronal Intranuclear Inclusion Disease-Related Disorders', 'Neuroprotection by IFN-γ via astrocyte-secreted IL-6 in acute neuroinflammation', and 'Anti-Citrullinated Protein Antibodies Induce Macrophage Subset Disequilibrium in RA Patients'.
Oxidative phosphorylation regulates B cell effector cytokines and promotes inflammation in multiple sclerosis
IRGM promotes the PINK1‐mediated mitophagy through the degradation of Mitofilin in SH‐SY5Y cells
IRGM promotes melanoma cell survival through autophagy and is a promising prognostic biomarker for clinical application
Irgm1 knockout indirectly inhibits regeneration after skeletal muscle injury in mice
Expansion of Human-Specific GGC Repeat in Neuronal Intranuclear Inclusion Disease-Related Disorders
Neuroprotection by IFN-γ<i>via</i>astrocyte-secreted IL-6 in acute neuroinflammation
GFI1 downregulation promotes inflammation-linked metastasis of colorectal cancer
Intravenous Administration of Adipose-Derived Stem Cell Protein Extracts Improves Neurological Deficits in a Rat Model of Stroke
Irgm1 suppresses NLRP3 Inflammasome-mediated IL-1β production
Irgm1 promotes M1 but not M2 macrophage polarization in atherosclerosis pathogenesis and development
MicroRNA 182 inhibits CD4+CD25+Foxp3+ Treg differentiation in experimental autoimmune encephalomyelitis
Irgm1 is required for the inflammatory function of M1 macrophage in early experimental autoimmune encephalomyelitis
Anti-Citrullinated Protein Antibodies Induce Macrophage Subset Disequilibrium in RA Patients
IFNg-induced Irgm1 promotes tumorigenesis of melanoma via dual regulation of apoptosis and Bif-1-dependent autophagy
IRGM1 enhances B16 melanoma cell metastasis through PI3K-Rac1 mediated epithelial mesenchymal transition
Circulating microparticles in patients with coronary heart disease and its correlation with interleukin-6 and C-reactive protein
Neuroprotection effect of interleukin (IL)-17 secreted by reactive astrocytes is emerged from a high-level IL-17-containing environment during acute neuroinflammation
IRGM1 regulates oxidized LDL uptake by macrophage via actin-dependent receptor internalization during atherosclerosis
Immune-related GTPase M (IRGM1) regulates neuronal autophagy in a mouse model of stroke
Immune-related GTPase Irgm1 exacerbates experimental auto-immune encephalomyelitis by promoting the disruption of blood–brain barrier and blood–cerebrospinal fluid barrier