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Michal Slyper

Broad Institute ·
Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include Single-cell and spatial transcriptomics, Cancer Genomics and Diagnostics, Cancer Cells and Metastasis, and RNA modifications and cancer.
h-index
29
citations
10,582
works
89
NIH funding
primary concept
Biology
email

Recent publications

Multi-modal skin atlas identifies a multicellular immune-stromal community associated with disrupted cornification and specific T cell expansion in atopic dermatitis
Nature Communications 2026cited by 1position: middledoi
A single-nucleus and spatial transcriptomic atlas of the COVID-19 liver reveals topological, functional, and regenerative organ disruption in patients
Genome biology 2025cited by 6position: middledoi
A cellular and spatial atlas of TP53-associated tissue remodeling defines a multicellular tumor ecosystem in lung adenocarcinoma
Nature Cancer 2025cited by 6position: middledoi
SlideCNA: spatial copy number alteration detection from Slide-seq-like spatial transcriptomics data
Genome biology 2025cited by 1position: middledoi
Author Correction: A multi-modal single-cell and spatial expression map of metastatic breast cancer biopsies across clinicopathological features
Nature Medicine 2025cited by 0position: middledoi
A multi-modal single-cell and spatial expression map of metastatic breast cancer biopsies across clinicopathological features
Nature Medicine 2024cited by 70position: middledoi
Protective role for kidney TREM2 macrophages in obesity- and diabetes-induced kidney injury
Cell Reports 2024cited by 41position: middledoi
N-acetylneuraminic acid links immune exhaustion and accelerated memory deficit in diet-induced obese Alzheimer’s disease mouse model
Nature Communications 2023cited by 45position: middledoi
Inference of single cell profiles from histology stains with the Single Cell omics from Histology Analysis Framework (SCHAF)
bioRxiv (Cold Spring Harbor Laboratory) 2023cited by 36position: middledoi
A cellular and spatial atlas of <i>TP53</i> -associated tissue remodeling in lung adenocarcinoma
bioRxiv (Cold Spring Harbor Laboratory) 2023cited by 5position: middledoi
Single-cell RNA-seq reveals cell type–specific molecular and genetic associations to lupus
Science 2022cited by 524position: middledoi
Single-nucleus cross-tissue molecular reference maps toward understanding disease gene function
Science 2022cited by 419position: middledoi
Abstract PD6-03: Spatio-molecular dissection of the breast cancer metastatic microenvironment
Cancer Research 2022cited by 1position: middledoi
COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets
Nature 2021cited by 875position: middledoi
Expansion sequencing: Spatially precise in situ transcriptomics in intact biological systems
Science 2021cited by 410position: middledoi
Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics
Nature Medicine 2021cited by 372position: middledoi
Single‐Cell, Single‐Nucleus, and Spatial RNA Sequencing of the Human Liver Identifies Cholangiocyte and Mesenchymal Heterogeneity
Hepatology Communications 2021cited by 278position: middledoi
Skin-resident innate lymphoid cells converge on a pathogenic effector state
Nature 2021cited by 204position: middledoi
A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors
Nature Medicine 2020cited by 790position: firstdoi
A single-cell landscape of high-grade serous ovarian cancer
Nature Medicine 2020cited by 518position: middledoi
snRNA-seq reveals a subpopulation of adipocytes that regulates thermogenesis
Nature 2020cited by 365position: middledoi
Cumulus provides cloud-based data analysis for large-scale single-cell and single-nucleus RNA-seq
Nature Methods 2020cited by 264position: middledoi
Integrated scRNA-Seq Identifies Human Postnatal Thymus Seeding Progenitors and Regulatory Dynamics of Differentiating Immature Thymocytes
Immunity 2020cited by 140position: middledoi
Author Correction: A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors
Nature Medicine 2020cited by 30position: firstdoi
Expansion Sequencing: Spatially Precise <i>In Situ</i> Transcriptomics in Intact Biological Systems
bioRxiv (Cold Spring Harbor Laboratory) 2020cited by 29position: middledoi
Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis
Cell 2019cited by 1,418position: middledoi
Decoding human fetal liver haematopoiesis
Nature 2019cited by 630position: middledoi
Single cell census of human kidney organoids shows reproducibility and diminished off-target cells after transplantation
Nature Communications 2019cited by 218position: middledoi
A revised airway epithelial hierarchy includes CFTR-expressing ionocytes
Nature 2018cited by 1,247position: middledoi
Axes of differentiation in breast cancer: untangling stemness, lineage identity, and the epithelial to mesenchymal transition
WIREs Systems Biology and Medicine 2013cited by 23position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Aviv Regev · Moscow Institute of Thermal Technology8 papers (2019–2025)Orit Rozenblatt–Rosen · Broad Institute5 papers (2020–2025)Åsa Segerstolpe · Broad Institute4 papers (2021–2025)Orr Ashenberg · Broad Institute4 papers (2020–2025)Bo Li · Yuhuangding Hospital3 papers (2020–2023)Julia Waldman · Broad Institute3 papers (2019–2025)Judit Jané‐Valbuena · Broad Institute3 papers (2023–2025)Scott J. Rodig · Massachusetts Institute of Technology3 papers (2023–2025)Daniel L. Abravanel · Harvard University2 papers (2023–2025)Johanna Klughammer · LMU Klinikum2 papers (2023–2025)Yiming Yang · Southwest Petroleum University2 papers (2020–2023) · 2 papers (2020–2020)Sébastien Vigneau · Ginkgo Bioworks, Inc. (United States)2 papers (2023–2023)Danielle Dionne · Broad Institute2 papers (2019–2020)Anna Greka · Broad Institute2 papers (2019–2023)Timothy L. Tickle · Broad Institute2 papers (2020–2020)Roy Z. Granit · Hebrew University of Jerusalem2 papers (2012–2013) · 2 papers (2019–2023)Kathleen L. Pfaff · Harvard Stem Cell Institute2 papers (2023–2023)Ittai Ben‐Porath · Hebrew University of Jerusalem2 papers (2012–2013)