Area of research
Molecular Biology · Pulmonary and Respiratory Medicine
Research interest
Research interests include Epigenetics and DNA Methylation, Prostate Cancer Treatment and Research, RNA modifications and cancer, and Mechanisms of cancer metastasis.
MammOnc-DB, an integrative breast cancer data analysis platform for target discovery
C/EBPβ increases tumor aggressiveness by enhancing KIFC1 expression in androgen receptor negative triple negative breast cancer
HDAC7 promotes renal cancer progression by reprogramming branched-chain amino acid metabolism
Combination of dual JAK/HDAC inhibitor with regorafenib synergistically reduces tumor growth, metastasis, and regorafenib-induced toxicity in colorectal cancer
Bromodomain inhibitor treatment leads to overexpression of multiple kinases in cancer cells
Systemic Anti-Inflammatory Therapy Aided by Curcumin-Laden Double-Headed Nanoparticles Combined with Injectable Long-Acting Insulin in a Rodent Model of Diabetes Eye Disease
Global impact of somatic structural variation on the cancer proteome
A hybrid breast cancer/mesenchymal stem cell population enhances chemoresistance and metastasis
Targeting of oncogenic AAA-ATPase TRIP13 reduces progression of pancreatic ductal adenocarcinoma
BZW2 Inhibition Reduces Colorectal Cancer Growth and Metastasis
The effect of paclitaxel- and fisetin-loaded PBM nanoparticles on apoptosis and reversal of drug resistance gene ABCG2 in ovarian cancer
Microbiome diversity in African American, European American, and Egyptian colorectal cancer patients
UALCAN: An update to the integrated cancer data analysis platform
Proteogenomic characterization of 2002 human cancers reveals pan-cancer molecular subtypes and associated pathways
ARID1A-deficient bladder cancer is dependent on PI3K signaling and sensitive to EZH2 and PI3K inhibitors
DCZ0415, a small‐molecule inhibitor targeting TRIP13, inhibits EMT and metastasis via inactivation of the FGFR4/STAT3 axis and the Wnt/β‐catenin pathway in colorectal cancer
Mass-spectrometry-based proteomic correlates of grade and stage reveal pathways and kinases associated with aggressive human cancers
The TGF-β/HDAC7 axis suppresses TCA cycle metabolism in renal cancer
Comparative analysis of triple-negative breast cancer transcriptomics of Kenyan, African American and Caucasian Women
Collagen modifying enzyme P4HA1 is overexpressed and plays a role in lung adenocarcinoma
Comparative transcriptome analyses reveal genes associated with SARS-CoV-2 infection of human lung epithelial cells
MS4A3 promotes differentiation in chronic myeloid leukemia by enhancing common β-chain cytokine receptor endocytosis
Global molecular alterations involving recurrence or progression of pediatric brain tumors
EZH2-Targeted Therapies in Cancer: Hype or a Reality
TRIP13 promotes metastasis of colorectal cancer regardless of p53 and microsatellite instability status
PAICS, a Purine Nucleotide Metabolic Enzyme, is Involved in Tumor Growth and the Metastasis of Colorectal Cancer
Targeting P4HA1 with a Small Molecule Inhibitor in a Colorectal Cancer PDX Model
PRDM16 suppresses HIF-targeted gene expression in kidney cancer
PAICS, a De Novo Purine Biosynthetic Enzyme, Is Overexpressed in Pancreatic Cancer and Is Involved in Its Progression
14-3-3 proteins protect AMPK-phosphorylated ten-eleven translocation-2 (TET2) from PP2A-mediated dephosphorylation