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Roman Laddach

Guy's Hospital ·
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Area of research
Oncology · Radiology, Nuclear Medicine and Imaging
Research interest
Research interests include HER2/EGFR in Cancer Research, Monoclonal and Polyclonal Antibodies Research, Lung Cancer Treatments and Mutations, and Cancer Genomics and Diagnostics.
h-index
13
citations
749
works
95
NIH funding
primary concept
email

Recent publications

Matrix mechano-sensing at the invasive front induces a cytoskeletal and transcriptional memory supporting metastasis
Nature Communications 2025cited by 28position: middledoi
Hyperinflammatory repolarisation of ovarian cancer patient macrophages by anti-tumour IgE antibody, MOv18, restricts an immunosuppressive macrophage:Treg cell interaction
Nature Communications 2025cited by 13position: middledoi
Linking Skin and Joint Inflammation in Psoriatic Arthritis through Shared CD8 <sup>+</sup> T Cell Clones
Arthritis & Rheumatology 2025cited by 9position: middledoi
Anti-EGFR Antibody–Drug Conjugate Carrying an Inhibitor Targeting CDK Restricts Triple-Negative Breast Cancer Growth
Clinical Cancer Research 2024cited by 27position: middledoi
Anti-cancer pro-inflammatory effects of an IgE antibody targeting the melanoma-associated antigen chondroitin sulfate proteoglycan 4
Nature Communications 2023cited by 40position: middledoi
B cell profiles, antibody repertoire and reactivity reveal dysregulated responses with autoimmune features in melanoma
Nature Communications 2023cited by 38position: middledoi
Folate receptor alpha in ovarian cancer tissue and patient serum is associated with disease burden and treatment outcomes
British Journal of Cancer 2022cited by 79position: middledoi
Enriched circulating and tumor-resident TGF-β <sup>+</sup> regulatory B cells in patients with melanoma promote FOXP3 <sup>+</sup> Tregs
OncoImmunology 2022cited by 38position: middledoi
Combined anti‐PD‐1 and anti‐CTLA‐4 checkpoint blockade: Treatment of melanoma and immune mechanisms of action
European Journal of Immunology 2021cited by 195position: middledoi
Tumor-Infiltrating B Lymphocyte Profiling Identifies IgG-Biased, Clonally Expanded Prognostic Phenotypes in Triple-Negative Breast Cancer
Cancer Research 2021cited by 97position: middledoi
B Cells in Patients With Melanoma: Implications for Treatment With Checkpoint Inhibitor Antibodies
Frontiers in Immunology 2021cited by 68position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Sophia N. Karagiannis · Guy's Hospital4 papers (2021–2024)Anthony Cheung · King's College London4 papers (2021–2024)Sophia Tsoka · King's College London4 papers (2021–2024)Katie E. Lacy · King's College London3 papers (2021–2022)Zena Willsmore · King's College London3 papers (2021–2022)R. J. C. Harris · Adaptimmune (United Kingdom)3 papers (2021–2022)Ciaran Healy · St Thomas' Hospital3 papers (2021–2022)Silvia Crescioli · King's College London3 papers (2021–2022)Alicia M. Chenoweth · Guy's Hospital3 papers (2021–2024)Alastair D. MacKenzie Ross · St Thomas' Hospital3 papers (2021–2022)Jenny L. C. Geh · St Thomas' Hospital3 papers (2021–2022)James Spicer · King's College London3 papers (2021–2022)Ricarda M. Hoffmann · Institute of Cancer Research3 papers (2021–2024)Jitesh Chauhan · King's College London3 papers (2021–2022)Sophie Papa · The London College2 papers (2021–2021)Alexa McCraw · Guy's Hospital2 papers (2021–2021)Gabriel Osborn · Guy's Hospital2 papers (2021–2021)Heather J. Bax · King's College London2 papers (2021–2021)Mano Nakamura · Guy's Hospital2 papers (2021–2021)Sheeba Irshad · King's College London1 papers (2024–2024)
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