Area of research
Physiology · Molecular Biology
Research interest
Research interests include Alzheimer's disease research and treatments, Protein Structure and Dynamics, RNA and protein synthesis mechanisms, and HIV Research and Treatment.
Low complexity domains of the nucleocapsid protein of SARS-CoV-2 form amyloid fibrils
De novo designed protein inhibitors of amyloid aggregation and seeding
Structure-based inhibitors of amyloid beta core suggest a common interface with tau
Atomic structures of fibrillar segments of hIAPP suggest tightly mated β-sheets are important for cytotoxicity
Common fibrillar spines of amyloid-β and human islet amyloid polypeptide revealed by microelectron diffraction and structure-based inhibitors
Fabs Enable Single Particle cryoEM Studies of Small Proteins