Area of research
Spectroscopy · Molecular Biology
Research interest
Research focused on Enzyme and Biosynthesis, with related work in ATP synthase, In silico, Farnesyl diphosphate synthase. Notable publications include 'The Mevalonate Pathway Is a Druggable Target for Vaccine Adjuvant Discovery', 'Antiinfectives targeting enzymes and the proton motive force', and 'Reduced cell proliferation by IKK2 depletion in a mouse lung-cancer model'.
Distinct Energy-Coupling Factor Transporter Subunits Enable Flavin Acquisition and Extracytosolic Trafficking for Extracellular Electron Transfer in Listeria monocytogenes
Mycobacterium tuberculosis releases an antacid that remodels phagosomes
The Mevalonate Pathway Is a Druggable Target for Vaccine Adjuvant Discovery
Spectroscopic and Computational Investigations of Ligand Binding to IspH: Discovery of Non‐diphosphate Inhibitors
Dynamic Structure and Inhibition of a Malaria Drug Target: Geranylgeranyl Diphosphate Synthase
Antiinfectives targeting enzymes and the proton motive force
Bioorganometallic Chemistry with IspG and IspH: Structure, Function, and Inhibition of the [Fe<sub>4</sub>S<sub>4</sub>] Proteins Involved in Isoprenoid Biosynthesis
Undecaprenyl Diphosphate Synthase Inhibitors: Antibacterial Drug Leads
Taxodione and arenarone inhibit farnesyl diphosphate synthase by binding to the isopentenyl diphosphate site
A Molecular Dynamics Investigation of <i>Mycobacterium tuberculosis</i> Prenyl Synthases: Conformational Flexibility and Implications for Computer‐aided Drug Discovery
Farnesyl Diphosphate Synthase Inhibitors from<i>In Silico</i>Screening
Reduced cell proliferation by IKK2 depletion in a mouse lung-cancer model
Antibacterial drug leads targeting isoprenoid biosynthesis