Area of research
Cellular and Molecular Neuroscience · Molecular Biology
Research interest
Research interests include Receptor Mechanisms and Signaling, Neuroscience and Neuropharmacology Research, Neurotransmitter Receptor Influence on Behavior, and Advanced Fluorescence Microscopy Techniques.
The sound of neural silence.
Meningeal regulatory T cells inhibit nociception in female mice
Meningeal regulatory T cells inhibit nociception in female mice.
Changes in neurotensin signalling drive hedonic devaluation in obesity
Thalamic opioids from POMC satiety neurons switch on sugar appetite.
Changes in neurotensin signalling drive hedonic devaluation in obesity.
Absolute measurement of fast and slow neuronal signals with fluorescence lifetime photometry at high temporal resolution
Hunger modulates exploration through suppression of dopamine signaling in the tail of the striatum
Sensitive dLight for imaging broad-spectrum dopamine events across brain regions
Top-down control of the descending pain modulatory system drives placebo analgesia
Unlocking opioid neuropeptide dynamics with genetically encoded biosensors
Unlocking opioid neuropeptide dynamics with genetically encoded biosensors.
Isolation of psychedelic-responsive neurons underlying anxiolytic behavioral states.
Phasic locus coeruleus activity enhances trace fear conditioning by increasing dopamine release in the hippocampus.
Targeted micro-fiber arrays for measuring and manipulating localized multi-scale neural dynamics over large, deep brain volumes during behavior
Phasic locus coeruleus activity enhances trace fear conditioning by increasing dopamine release in the hippocampus
Dopamine release plateau and outcome signals in dorsal striatum contrast with classic reinforcement learning formulations.
5-HT_FAsTR: a versatile, label-free, high-throughput, fluorescence-based microplate assay to quantify serotonin transport and release.
Psychedelics promote neuroplasticity through the activation of intracellular 5-HT2A receptors.
Adeno-associated viral vectors for functional intravenous gene transfer throughout the non-human primate brain
Adeno-associated viral vectors for functional intravenous gene transfer throughout the non-human primate brain.
Distinct sub-second dopamine signaling in dorsolateral striatum measured by a genetically-encoded fluorescent sensor.
Behavioral encoding across timescales by region-specific dopamine dynamics.
Sexual differentiation of neural mechanisms of stress sensitivity during puberty.
Lighting up action potentials with fast and bright voltage sensors.
Intravenous functional gene transfer throughout the brain of non-human primates using AAV
Intravenous functional gene transfer throughout the brain of non-human primates using AAV
Competition between stochastic neuropeptide signals calibrates the rate of satiation
Next-generation sequencing of AAV.CAP-Mac from Chuapoco et al. (2023) Nature Nanotechnology
Next-generation sequencing of AAV.CAP-Mac from Chuapoco et al. (2023) Nature Nanotechnology