Area of research
Immunology · Molecular Biology
Research interest
Research interests include Immune Cell Function and Interaction, Immune Response and Inflammation, Immunotherapy and Immune Responses, and T-cell and B-cell Immunology.
Control of adaptive immunity by pattern recognition receptors
Alloreactive memory CD4 T cells promote transplant rejection by engaging DCs to induce innate inflammation and CD8 T cell priming
Immune checkpoint blockade induces gut microbiota translocation that augments extraintestinal antitumor immunity
Effector memory T cells induce innate inflammation by triggering DNA damage and a non-canonical STING pathway in dendritic cells
IEC-intrinsic IL-1R signaling holds dual roles in regulating intestinal homeostasis and inflammation
Effector memory CD4<sup>+</sup> T cells induce damaging innate inflammation and autoimmune pathology by engaging CD40 and TNFR on myeloid cells.
TLR signaling adapter BCAP regulates inflammatory to reparatory macrophage transition by promoting histone lactylation
T cells instruct myeloid cells to produce inflammasome-independent IL-1β and cause autoimmunity
Regulatory polymorphisms modulate the expression of HLA class II molecules and promote autoimmunity
The DNA Sensor AIM2 Maintains Intestinal Homeostasis via Regulation of Epithelial Antimicrobial Host Defense
Toll-Like Receptors and Control of Adaptive Immunity