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John D. Carpten

City Of Hope National Medical Center · US
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Area of research
Cancer Research · Pulmonary and Respiratory Medicine
Research interest
Research interests include Cancer Genomics and Diagnostics, Prostate Cancer Treatment and Research, Multiple Myeloma Research and Treatments, and Epigenetics and DNA Methylation.
h-index
74
citations
30,178
works
735
NIH funding
primary concept
email

Recent publications

Somatic Genomic Profiling of Pancreatic Ductal Adenocarcinomas From a Diverse Cohort of Patients
Pancreas 2025cited by 9position: middledoi
Mutational landscape of triple-negative breast cancer in African American women
Nature Genetics 2025cited by 5position: lastdoi
Advancing genomics to improve health equity
Nature Genetics 2024cited by 49position: middledoi
Evidence of Novel Susceptibility Variants for Prostate Cancer and a Multiancestry Polygenic Risk Score Associated with Aggressive Disease in Men of African Ancestry
European Urology 2023cited by 49position: middledoi
Evaluating approaches for constructing polygenic risk scores for prostate cancer in men of African and European ancestry
The American Journal of Human Genetics 2023cited by 23position: middledoi
The T Cell Immunoscore as a Reference for Biomarker Development Utilizing Real-World Data from Patients with Advanced Malignancies Treated with Immune Checkpoint Inhibitors
Cancers 2023cited by 10position: middledoi
Evaluating Approaches for Constructing Polygenic Risk Scores for Prostate Cancer in Men of African and European Ancestry
medRxiv 2023cited by 2position: middledoi
African Ancestry–Associated Gene Expression Profiles in Triple-Negative Breast Cancer Underlie Altered Tumor Biology and Clinical Outcome in Women of African Descent
Cancer Discovery 2022cited by 132position: middledoi
A Rare Germline HOXB13 Variant Contributes to Risk of Prostate Cancer in Men of African Ancestry
European Urology 2022cited by 47position: middledoi
Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry
The American Journal of Human Genetics 2021cited by 34position: middledoi
Single-cell sequencing of genomic DNA resolves sub-clonal heterogeneity in a melanoma cell line
Communications Biology 2020cited by 69position: middledoi
A Germline Variant at 8q24 Contributes to Familial Clustering of Prostate Cancer in Men of African Ancestry
European Urology 2020cited by 50position: middledoi
Two-stage Study of Familial Prostate Cancer by Whole-exome Sequencing and Custom Capture Identifies 10 Novel Genes Associated with the Risk of Prostate Cancer
European Urology 2020cited by 42position: middledoi
A meta-analysis of genome-wide association studies of multiple myeloma among men and women of African ancestry
Blood Advances 2020cited by 31position: middledoi
Temporospatial genomic profiling in glioblastoma identifies commonly altered core pathways underlying tumor progression
Neuro-Oncology Advances 2020cited by 31position: middledoi
Abstract C050: Deleterious coding variants in African American Hereditary Prostate Cancer Study (AAHPC) families
Cancer Epidemiology Biomarkers & Prevention 2020cited by 0position: middledoi
Resolving sub-clonal heterogeneity within cell-line growths by single cell sequencing genomic DNA
bioRxiv (Cold Spring Harbor Laboratory) 2019cited by 4position: middledoi
Lack of<i>APC</i>somatic mutation is associated with early-onset colorectal cancer in African Americans
Carcinogenesis 2018cited by 39position: middledoi
E6201, an intravenous MEK1 inhibitor, achieves an exceptional response in BRAF V600E-mutated metastatic malignant melanoma with brain metastases
Investigational New Drugs 2018cited by 27position: middledoi
Two Novel Susceptibility Loci for Prostate Cancer in Men of African Ancestry
JNCI Journal of the National Cancer Institute 2017cited by 88position: middledoi
Comprehensive molecular profiling of 718 Multiple Myelomas reveals significant differences in mutation frequencies between African and European descent cases
PLoS Genetics 2017cited by 86position: lastdoi
Prospective Feasibility Trial for Genomics-Informed Treatment in Recurrent and Progressive Glioblastoma
Clinical Cancer Research 2017cited by 81position: middledoi
A multicenter, randomized study of decitabine as epigenetic priming with induction chemotherapy in children with AML
Clinical Epigenetics 2017cited by 44position: middledoi
REVEL: An Ensemble Method for Predicting the Pathogenicity of Rare Missense Variants
The American Journal of Human Genetics 2016cited by 2,933position: middledoi
Prostate Cancer Susceptibility in Men of African Ancestry at 8q24
JNCI Journal of the National Cancer Institute 2016cited by 136position: middledoi
Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation
Nature Communications 2016cited by 58position: middledoi
A Meta-analysis of Multiple Myeloma Risk Regions in African and European Ancestry Populations Identifies Putatively Functional Loci
Cancer Epidemiology Biomarkers & Prevention 2016cited by 30position: middledoi
Toward precision medicine in glioblastoma: the promise and the challenges
Neuro-Oncology 2015cited by 222position: middledoi
Integration of multiethnic fine-mapping and genomic annotation to prioritize candidate functional SNPs at prostate cancer susceptibility regions
Human Molecular Genetics 2015cited by 41position: middledoi
Pilot Trial of Selecting Molecularly Guided Therapy for Patients with Non–V600 BRAF-Mutant Metastatic Melanoma: Experience of the SU2C/MRA Melanoma Dream Team
Molecular Cancer Therapeutics 2015cited by 27position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

David W. Craig · City Of Hope National Medical Center11 papers (2012–2025) · 6 papers (2013–2020)Jeffrey M. Trent · Translational Genomics Research Institute4 papers (2015–2020)Carmen Gómez · University of Miami3 papers (2012–2014) · 3 papers (2012–2014) · 3 papers (2012–2014)Sara A. Byron · Translational Genomics Research Institute3 papers (2015–2020) · 3 papers (2019–2025)Mark D. Pegram · Stanford University3 papers (2012–2014)Ian T. Fiddes · 10X Genomics (United States)2 papers (2019–2020)Jonathan J. Keats · Phoenix (United States)2 papers (2013–2017) · 2 papers (2017–2018)Vijay Kumar · Pennsylvania State University2 papers (2019–2020) · 2 papers (2017–2020) · 2 papers (2012–2014)Nhan L. Tran · Mayo Clinic in Arizona2 papers (2015–2020)Raoul Tibes · New York University2 papers (2014–2018)Joanna J. Phillips · UCSF Helen Diller Family Comprehensive Cancer Center2 papers (2015–2020)Timothy J. Triche · RF Laboratories (United States)2 papers (2017–2018) · 2 papers (2019–2020)
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