Area of research
Rheumatology · Molecular Biology
Research interest
Research focused on Cancer cell and Myeloid leukemia, with related work in Temozolomide, DNA, Computational biology. Notable publications include 'MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool', 'A comprehensive structural, biochemical and biological profiling of the human NUDIX hydrolase family', and 'Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress'.
Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress
A Patient-Derived Cell Atlas Informs Precision Targeting of Glioblastoma
A comprehensive structural, biochemical and biological profiling of the human NUDIX hydrolase family
MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool