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Rita Shaknovich

Meta (United States) · US
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Area of research
Molecular Biology · Pathology and Forensic Medicine
Research interest
Research interests include Lymphoma Diagnosis and Treatment, Epigenetics and DNA Methylation, Cancer-related gene regulation, and Cancer Genomics and Diagnostics.
h-index
47
citations
8,619
works
194
NIH funding
primary concept
email

Recent publications

Evaluating the analytical validity of circulating tumor DNA sequencing assays for precision oncology
Nature Biotechnology 2021cited by 258position: middledoi
TET2 Deficiency Causes Germinal Center Hyperplasia, Impairs Plasma Cell Differentiation, and Promotes B-cell Lymphomagenesis
Cancer Discovery 2018cited by 164position: middledoi
Histone demethylase LSD1 is required for germinal center formation and BCL6-driven lymphomagenesis
Nature Immunology 2018cited by 93position: middledoi
AICDA drives epigenetic heterogeneity and accelerates germinal center-derived lymphomagenesis
Nature Communications 2018cited by 74position: lastdoi
<i>CREBBP</i> Inactivation Promotes the Development of HDAC3-Dependent Lymphomas
Cancer Discovery 2016cited by 269position: middledoi
EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis
Cancer Cell 2016cited by 249position: middledoi
Rationally designed BCL6 inhibitors target activated B cell diffuse large B cell lymphoma
Journal of Clinical Investigation 2016cited by 172position: middledoi
miR-181a negatively regulates NF-κB signaling and affects activated B-cell–like diffuse large B-cell lymphoma pathogenesis
Blood 2016cited by 49position: middledoi
The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development
Nature Medicine 2015cited by 442position: middledoi
TET1 is a tumor suppressor of hematopoietic malignancy
Nature Immunology 2015cited by 226position: middledoi
Epigenomic evolution in diffuse large B-cell lymphomas
Nature Communications 2015cited by 128position: middledoi
DNA Methylation Dynamics of Germinal Center B Cells Are Mediated by AID
Cell Reports 2015cited by 105position: lastdoi
IL10 receptor is a novel therapeutic target in DLBCLs
Leukemia 2015cited by 72position: lastdoi
CTCF Haploinsufficiency Destabilizes DNA Methylation and Predisposes to Cancer
Cell Reports 2014cited by 184position: middledoi
Variability in DNA methylation defines novel epigenetic subgroups of DLBCL associated with different clinical outcomes
Blood 2014cited by 108position: lastdoi
EZH2 Is Required for Germinal Center Formation and Somatic EZH2 Mutations Promote Lymphoid Transformation
Cancer Cell 2013cited by 838position: middledoi
Mechanism-Based Epigenetic Chemosensitization Therapy of Diffuse Large B-Cell Lymphoma
Cancer Discovery 2013cited by 214position: middledoi
Aberration in DNA Methylation in B-Cell Lymphomas Has a Complex Origin and Increases with Disease Severity
PLoS Genetics 2013cited by 123position: middledoi
Downregulation of FOXP1 is required during germinal center B-cell function
Blood 2013cited by 65position: middledoi
MALT1 Small Molecule Inhibitors Specifically Suppress ABC-DLBCL In Vitro and In Vivo
Cancer Cell 2012cited by 257position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Ari Melnick · Cornell University13 papers (2012–2018)Olivier Elemento · Cornell University7 papers (2013–2018)Huimin Geng · University of California, San Francisco6 papers (2013–2018)Randy D. Gascoyne · BC Cancer Agency6 papers (2013–2018)Leandro Cerchietti · Cornell University5 papers (2012–2016)Giorgio Inghirami · Cornell University4 papers (2013–2018)David W. Scott · BC Cancer Agency4 papers (2013–2018)Matt Teater · Cornell University4 papers (2014–2018)Matthías Kormáksson · Novartis (Switzerland)4 papers (2013–2015)Wendy Béguelin · Cornell University3 papers (2015–2016)Yanwen Jiang · University College London3 papers (2013–2015)Nyasha Chambwe · Northwell Health3 papers (2014–2015)Katerina Hatzi · Cornell University3 papers (2016–2018)David Redmond · Cornell University3 papers (2015–2018)Mariano Cárdenas · Cornell University3 papers (2016–2018)Lucy A. Godley · Northwestern University3 papers (2013–2015)Wayne Tam · Donald & Barbara Zucker School of Medicine at Hofstra/Northwell3 papers (2013–2016)Iannis Aifantis · NYU Langone Health2 papers (2015–2018)Franziska Michor · Harvard University2 papers (2013–2014)Hao Shen · Tongji University2 papers (2016–2018)
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