Area of research
Molecular Biology · Epidemiology
Research interest
Research focused on Insertional mutagenesis and Chromatin, with related work in Autophagy, Neuroprotection, Pars compacta. Notable publications include 'UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programs', 'Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing', and 'Unravelling cell type-specific responses to Parkinson’s Disease at single cell resolution'.
Unravelling cell type-specific responses to Parkinson’s Disease at single cell resolution
HNRNPH1 regulates the neuroprotective cold‐shock protein RBM3 expression through poison exon exclusion
Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing
UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programs
SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4
A single-copy Sleeping Beauty transposon mutagenesis screen identifies new PTEN-cooperating tumor suppressor genes
A conditional piggyBac transposition system for genetic screening in mice identifies oncogenic networks in pancreatic cancer