Area of research
Organic Chemistry · Pharmacology
Research interest
Research focused on Total synthesis and Enantioselective synthesis, with related work in Stereochemistry, Electrophile, Aspidosperma. Notable publications include 'Pd(II)-Catalyzed meta -C–H Olefination, Arylation, and Acetoxylation of Indolines Using a U-Shaped Template', 'Biogenetically-Inspired Total Synthesis of Epidithiodiketopiperazines and Related Alkaloids', and 'A Concise and Versatile Double‐Cyclization Strategy for the Highly Stereoselective Synthesis and Arylative Dimerization of Aspidosperma Alkaloids'.
Total Synthesis of (−)-Owerreine and (−)-Anhydrovobtusine
Total synthesis of himastatin
Structure and Function of NzeB, a Versatile C–C and C–N Bond-Forming Diketopiperazine Dimerase
Total Synthesis and Anti-Cancer Activity of All Known Communesin Alkaloids and Related Derivatives
Synthesis of Antibiotics and Related Molecules
Concise Synthesis of (−)-Hodgkinsine, (−)-Calycosidine, (−)-Hodgkinsine B, (−)-Quadrigemine C, and (−)-Psycholeine via Convergent and Directed Modular Assembly of Cyclotryptamines
Convergent and Biomimetic Enantioselective Total Synthesis of (−)-Communesin F
Concise Total Syntheses of (+)-Haplocidine and (+)-Haplocine via Late-Stage Oxidation of (+)-Fendleridine Derivatives
Concise Total Synthesis of (+)-Asperazine, (+)-Pestalazine A, and (+)-<i>iso</i>-Pestalazine A. Structure Revision of (+)-Pestalazine A
The fibroblast Tiam1-osteopontin pathway modulates breast cancer invasion and metastasis
ChemInform Abstract: Concise Total Synthesis of (+)‐Asperazine, (+)‐Pestalazine A, and (+)‐iso‐Pestalazine A. Structure Revision of (+)‐Pestalazine A.
Biogenetically-Inspired Total Synthesis of Epidithiodiketopiperazines and Related Alkaloids
Direct Observation of Intermediates Involved in the Interruption of the Bischler–Napieralski Reaction
ChemInform Abstract: Concise and Enantioselective Total Synthesis of (‐)‐Mehranine, (‐)‐Methylenebismehranine, and Related Aspidosperma Alkaloids.
ChemInform Abstract: C7‐Derivatization of C3‐Alkylindoles Including Tryptophans and Tryptamines.
Pd(II)-Catalyzed <i>meta</i>-C–H Olefination, Arylation, and Acetoxylation of Indolines Using a U-Shaped Template
C7-Derivatization of C3-Alkylindoles Including Tryptophans and Tryptamines
Concise and Enantioselective Total Synthesis of (−)‐Mehranine, (−)‐Methylenebismehranine, and Related <i>Aspidosperma</i> Alkaloids
ChemInform Abstract: Total Synthesis, Stereochemical Assignment, and Biological Activity of All Known (‐)‐Trigonoliimines.
ChemInform Abstract: Robinson′s Landmark Synthesis of Tropinone
Application of diazene-directed fragment assembly to the total synthesis and stereochemical assignment of (+)-desmethyl-meso-chimonanthine and related heterodimeric alkaloids
Synthesis and anticancer activity of epipolythiodiketopiperazine alkaloids
Total Synthesis, Stereochemical Assignment, and Biological Activity of All Known (−)-Trigonoliimines
Robinson's landmark synthesis of tropinone
ChemInform Abstract: Synthesis of Spirocyclic Indoles by Interruption of the Bischler—Napieralski Reaction.
A Concise and Versatile Double‐Cyclization Strategy for the Highly Stereoselective Synthesis and Arylative Dimerization of Aspidosperma Alkaloids
Concise total synthesis of (+)-gliocladins B and C
ChemInform Abstract: Lithiation and Electrophilic Substitution of Dimethyl Triazones.
ChemInform Abstract: Radical‐Mediated Dimerization and Oxidation Reactions for the Synthesis of Complex Alkaloids
ChemInform Abstract: Concise Total Synthesis and Stereochemical Revision of (+)‐Naseseazines A and B: Regioselective Arylative Dimerization of Diketopiperazine Alkaloids.