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Dustin S. Siegel

Massachusetts Institute of Technology · US
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Area of research
Infectious Diseases · Epidemiology
Research interest
Research interests include Chemistry, Virology, Coronavirus, Ebola virus, Virus, and Tryptamines.
h-index
citations
5,612
works
8
NIH funding
primary concept
email

Recent publications

Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease
mBio 2018cited by 1,510position: middledoi
Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses
Science Translational Medicine 2017cited by 1,628position: middledoi
Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo[2,1-<i>f</i>][triazin-4-amino] Adenine <i>C</i>-Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses
Journal of Medicinal Chemistry 2017cited by 659position: firstdoi
Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys
Nature 2016cited by 1,589position: middledoi
Discovery of an Oral Respiratory Syncytial Virus (RSV) Fusion Inhibitor (GS-5806) and Clinical Proof of Concept in a Human RSV Challenge Study
Journal of Medicinal Chemistry 2015cited by 124position: middledoi
ChemInform Abstract: C7‐Derivatization of C3‐Alkylindoles Including Tryptophans and Tryptamines.
ChemInform 2015cited by 0position: middledoi
C7-Derivatization of C3-Alkylindoles Including Tryptophans and Tryptamines
The Journal of Organic Chemistry 2014cited by 102position: middledoi
ChemInform Abstract: Lithiation and Electrophilic Substitution of Dimethyl Triazones.
ChemInform 2012cited by 0position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Mohammad Movassaghi · Massachusetts Institute of Technology3 papers (2012–2015)Timothy P. Sheahan · University of North Carolina at Chapel Hill2 papers (2017–2018)Richard L. Mackman · Gilead Sciences (United States)2 papers (2017–2018)Robert Jordan · University of Tennessee at Knoxville2 papers (2017–2018)Owen S. Fenton · Massachusetts Institute of Technology2 papers (2014–2015)Kazuma Amaike · Massachusetts Institute of Technology2 papers (2014–2015)Ralph S. Baric · University of North Carolina at Chapel Hill2 papers (2017–2018)Joy Y. Feng · Gilead Sciences (United States)2 papers (2017–2018)Rachel L. Graham · University of North Carolina at Chapel Hill2 papers (2017–2018)Tomáš Cihlář · Cambridge Health Alliance2 papers (2017–2018)Adrian S. Ray · Gilead Sciences (United States)2 papers (2017–2018)James Brett Case · University of Missouri–St. Louis2 papers (2017–2018)Richard P. Loach · Massachusetts Institute of Technology2 papers (2014–2015)Michael O. Clarke · Gilead Sciences (United States)2 papers (2017–2018)Amy Sims · Georgia State University2 papers (2017–2018)Erhan Özkal · Massachusetts Institute of Technology2 papers (2014–2015)Mark R. Denison · Bipar2 papers (2017–2018)Maria L. Agostini · VIR Biotechnology (United States)1 papers (2018–2018) · 1 papers (2018–2018)Yeojin Park · Gilead Sciences (United States)1 papers (2017–2017)
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