Area of research
Epidemiology · Molecular Biology
Research interest
Research interests include Autophagy in Disease and Therapy, Alzheimer's disease research and treatments, Inflammasome and immune disorders, and Ginseng Biological Effects and Applications.
Ocular-brain co-immunotherapy targeting amyloid-beta in Alzheimer's disease: Challenges and promising therapeutic avenues.
Ciliatoside A attenuates neuroinflammation in Alzheimer's disease by activating mitophagy and inhibiting NLRP3 inflammasome activation
Prosapogenin CP4 exacerbates mitophagy to induce apoptosis via AMPK-mTOR and PINK1/Parkin pathways in A549 cells
Anxiolytic effects of corilagin by targeting Htr2c through activation of the TrkB/CREB/BDNF pathway
14-3-3η Induces a Multidrug-Resistant Phenotype in Rheumatoid Arthritis via p53 Dysregulation: Insights from AIA Models
OGG1-driven pathogenesis in Kawasaki disease: Identification and pharmacological regulation of a molecular marker validated in transgenic mice and clinical models
Targeting calcium signaling in Alzheimer's disease: challenges and promising therapeutic avenues.
Activation of autophagy by Citri Reticulatae Semen extract ameliorates amyloid-beta-induced cell death and cognition deficits in Alzheimer's disease.
Pomiferin targets SERCA, mTOR, and P-gp to induce autophagic cell death in apoptosis-resistant cancer cells, and reverses the MDR phenotype in cisplatin-resistant tumors in vivo
Targeting Nrf2-Mediated Oxidative Stress Response in Traumatic Brain Injury: Therapeutic Perspectives of Phytochemicals.
Dietary Plant Polyphenols as the Potential Drugs in Neurodegenerative Diseases: Current Evidence, Advances, and Opportunities.
Traditional Patchouli essential oil modulates the host’s immune responses and gut microbiota and exhibits potent anti-cancer effects in Apc mice
Ferulic Acid Exerts Neuroprotective Effects via Autophagy Induction in <i>C. elegans</i> and Cellular Models of Parkinson's Disease.
Transcriptome Analysis of Immune Receptor Activation and Energy Metabolism Reduction as the Underlying Mechanisms in Interleukin-6-Induced Skeletal Muscle Atrophy
Targeting autophagy as a therapeutic strategy for identification of liganans from Peristrophe japonica in Parkinson's disease.
Synthesis, computational docking and biological evaluation of celastrol derivatives as dual inhibitors of SERCA and P-glycoprotein in cancer therapy
Inhibition of IL-6/JAK/STAT3 pathway rescues denervation-induced skeletal muscle atrophy
SERCA and P-glycoprotein inhibition and ATP depletion are necessary for celastrol-induced autophagic cell death and collateral sensitivity in multidrug-resistant tumor cells
Aspirin alleviates denervation-induced muscle atrophy via regulating the Sirt1/PGC-1α axis and STAT3 signaling
Adjuvant herbal therapy for targeting susceptibility genes to Kawasaki disease: An overview of epidemiology, pathogenesis, diagnosis and pharmacological treatment of Kawasaki disease.
Novel ginsenoside derivative 20(S)-Rh2E2 suppresses tumor growth and metastasis in vivo and in vitro via intervention of cancer cell energy metabolism.
Ca<sup>2+</sup> signalling plays a role in celastrol‐mediated suppression of synovial fibroblasts of rheumatoid arthritis patients and experimental arthritis in rats
Effect of Inulin-Type Carbohydrates on Insulin Resistance in Patients with Type 2 Diabetes and Obesity: A Systematic Review and Meta-Analysis.
Semi-synthetic isoflavones as BACE-1 inhibitors against Alzheimer’s disease
Critical role of histone demethylase Jumonji domain-containing protein 3 in the regulation of neointima formation following vascular injury
Mode of Action Analyses of Neferine, a Bisbenzylisoquinoline Alkaloid of Lotus (Nelumbo nucifera) against Multidrug-Resistant Tumor Cells
Pharmacogenomics of Scopoletin in Tumor Cells