Area of research
Hematology · Genetics
Research interest
Research interests include Acute Myeloid Leukemia Research, Myeloproliferative Neoplasms: Diagnosis and Treatment, Cancer Genomics and Diagnostics, and Multiple Myeloma Research and Treatments.
Acute megakaryoblastic leukaemia shows high frequency of chromosome 1q aberrations and dismal outcome
Risk Stratification of Patients with <i>RUNX1-</i>mutated Acute Myeloid Leukemia
Compartment-specific mutational landscape of clonal hematopoiesis
CHIP and hips: clonal hematopoiesis is common in patients undergoing hip arthroplasty and is associated with autoimmune disease
Characterization of Somatic Mosaicism and Mutational Profiling of Clonal Hematopoiesis Compared to MDS and sAML Depicts Diversities of Clonal Evolution
Validation and refinement of the revised 2017 European LeukemiaNet genetic risk stratification of acute myeloid leukemia
The clinical mutatome of core binding factor leukemia
Clinical presentation and differential splicing of SRSF2, U2AF1 and SF3B1 mutations in patients with acute myeloid leukemia
Clinical presentation and differential splicing of <i>SRSF2, U2AF1</i> and <i>SF3B1</i> mutations in patients with Acute Myeloid Leukaemia
Loss of KDM6A confers drug resistance in acute myeloid leukemia
Allelic Imbalance of Recurrently Mutated Genes in Acute Myeloid Leukaemia
Persistence of pre-leukemic clones during first remission and risk of relapse in acute myeloid leukemia
Genetics of acute myeloid leukemia in the elderly: mutation spectrum and clinical impact in intensively treated patients aged 75 years or older
Evolution of Cytogenetically Normal Acute Myeloid Leukemia During Therapy and Relapse: An Exome Sequencing Study of 50 Patients
Genetic heterogeneity of cytogenetically normal AML with mutations of CEBPA
Clonal heterogeneity of <i>FLT3</i>-ITD detected by high-throughput amplicon sequencing correlates with adverse prognosis in acute myeloid leukemia
Loss of KDM6A Confers Drug Resistance in Acute Myeloid Leukemia
NPM1 Variant Allele Frequency and Outcomes in AML
Clonal Evolution of Relapsed CBFB/MYH11 Rearranged Acute Myeloid Leukemia (AML)
A 29-gene and cytogenetic score for the prediction of resistance to induction treatment in acute myeloid leukemia
Persistence of pre-leukemic clones during first remission and risk of relapse in acute myeloid leukemia
Spectrum and prognostic relevance of driver gene mutations in acute myeloid leukemia
Adults with Philadelphia chromosome–like acute lymphoblastic leukemia frequently have <i>IGH-CRLF2</i> and <i>JAK2</i> mutations, persistence of minimal residual disease and poor prognosis
ZBTB7A mutations in acute myeloid leukaemia with t(8;21) translocation
Acute myeloid leukemia with del(9q) is characterized by frequent mutations of <i>NPM1</i>, <i>DNMT3A, WT1</i> and low expression of <i>TLE4</i>
PS29MRC - a Novel Predictive Score for Response to Therapy in Acute Myeloid Leukemia
Evolutionary Patterns of Cytogenetically Normal Acute Myeloid Leukemia Correlate with Time to Relapse
Comparison of FLT3-ITD Detection By High-Throughput Amplicon Sequencing to Routine Diagnostics - a Retrospective Analysis of AMLCG Study Patients
The target cell of transformation is distinct from the leukemia stem cell in murine CALM/AF10 leukemia models
DNMT3A Mutations Associate with Shorter Survival and Modulate the Prognostic Impact of Mutated NPM1: an Analysis Based on Comprehensive Mutational Screening of 660 AML Patients Treated on German AML Cooperative Group (AMLCG) Trials