Area of research
Hematology · Cancer Research
Research interest
Research interests include Acute Myeloid Leukemia Research, Cancer Genomics and Diagnostics, Acute Lymphoblastic Leukemia research, and Myeloproliferative Neoplasms: Diagnosis and Treatment.
Aberrant methylation limits antitumoral inflammation in lung adenocarcinoma by restricting RIPK3 expression
Enhancer Hijacking Discovery in Acute Myeloid Leukemia by Pyjacker Identifies MNX1 Activation via Deletion 7q
Lymphotoxin alpha eradicates acute myeloid leukemia and simultaneously promotes healthy hematopoiesis in mice
Molecular subgroups of T-cell acute lymphoblastic leukemia in adults treated according to pediatric-based GMALL protocols
Engineering an inducible leukemia-associated fusion protein enables large-scale ex vivo production of functional human phagocytes
Pyjacker identifies enhancer hijacking events in acute myeloid leukemia including <i>MNX1</i> activation via deletion 7q
In vivo PDX CRISPR/Cas9 screens reveal mutual therapeutic targets to overcome heterogeneous acquired chemo-resistance
Prevalence, Clinical and Molecular Features, and Prognostic Value of Tetraploidy/Near-Tetraploidy in Patients with Acute Myeloid Leukemia
DNA methylation epitypes highlight underlying developmental and disease pathways in acute myeloid leukemia
Fusion gene detection by RNA-sequencing complements diagnostics of acute myeloid leukemia and identifies recurring <i>NRIP1-MIR99AHG</i> rearrangements
Disease Modeling on Tumor Organoids Implicates AURKA as a Therapeutic Target in Liver Metastatic Colorectal Cancer
Mutations in <scp><i>HID1</i></scp> Cause Syndromic Infantile Encephalopathy and Hypopituitarism
Converting a leukemic transcription factor into a powerful tool for large-scale ex vivo production of human phagocytes
The clinical mutatome of core binding factor leukemia
Clonal evolution of acute myeloid leukemia from diagnosis to relapse
Loss of KDM6A confers drug resistance in acute myeloid leukemia
PAX5 biallelic genomic alterations define a novel subgroup of B-cell precursor acute lymphoblastic leukemia
DNA Methylation Profiling of AML Reveals Epigenetic Subgroups with Distinct Clinical Outcome
Gene Fusion Detection By RNA-Seq in Acute Myeloid Leukemia (AML)
Evolution of Cytogenetically Normal Acute Myeloid Leukemia During Therapy and Relapse: An Exome Sequencing Study of 50 Patients
Clonal heterogeneity of <i>FLT3</i>-ITD detected by high-throughput amplicon sequencing correlates with adverse prognosis in acute myeloid leukemia
Relapse of acute myeloid leukemia after allogeneic stem cell transplantation is associated with gain of <i>WT1</i> alterations and high mutation load
Clonal Evolution of Relapsed CBFB/MYH11 Rearranged Acute Myeloid Leukemia (AML)
Acute myeloid leukemia in the elderly is characterized by a distinct genetic and epigenetic landscape
Multi-Omics of Adult T Cell Acute Lymphoblastic Leukemia
Homocygous PAX5Sequence Mutations Define a Novel Subtype of B Cell Precursor Acute Lymphoblastic Leukemia
In-depth mutational analyses of colorectal neuroendocrine carcinomas with adenoma or adenocarcinoma components
Molecular alterations in bone marrow mesenchymal stromal cells derived from acute myeloid leukemia patients
ZBTB7A mutations in acute myeloid leukaemia with t(8;21) translocation
Acute myeloid leukemia with del(9q) is characterized by frequent mutations of <i>NPM1</i>, <i>DNMT3A, WT1</i> and low expression of <i>TLE4</i>