← back to search

John M. Sedivy

John Brown University · US
Area of research
Physiology · Aging
Research interest
Research interests include Telomeres, Telomerase, and Senescence, Genetics, Aging, and Longevity in Model Organisms, Cancer-related Molecular Pathways, and CRISPR and Genetic Engineering.
h-index
79
citations
32,742
works
259
NIH funding
primary concept
Biology
email

Recent publications

Retrotransposon Activation in the Aged and Alzheimer’s Disease Brain Examined by Nanopore Long-read DNA Sequencing
bioRxiv (Cold Spring Harbor Laboratory) 2025cited by 0position: lastdoi
Guidelines for minimal information on cellular senescence experimentation in vivo
Cell 2024cited by 262position: middledoi
Longevity biotechnology: bridging AI, biomarkers, geroscience and clinical applications for healthy longevity
Aging 2024cited by 37position: middledoi
Loss of epigenetic information as a cause of mammalian aging
Cell 2023cited by 601position: middledoi
Translational Significance of the LINE-1 Jumping Gene in Skeletal Muscle
Exercise and Sport Sciences Reviews 2022cited by 4position: middledoi
The role of retrotransposable elements in ageing and age-associated diseases
Nature 2021cited by 427position: lastdoi
Cellular Senescence: Defining a Path Forward
Cell 2019cited by 3,048position: middledoi
L1 drives IFN in senescent cells and promotes age-associated inflammation
Nature 2019cited by 1,228position: lastdoi
LINE1 Derepression in Aged Wild-Type and SIRT6-Deficient Mice Drives Inflammation
Cell Metabolism 2019cited by 492position: middledoi
Interventions to Slow Aging in Humans: Are We Ready?
Aging Cell 2015cited by 595position: middledoi

Grants

Presidential Young Investigator Awards
NSF9057715$275,0001990–1996PIRePORTER

Frequent collaborators

Vera Gorbunova · University of Rochester Medical Center4 papers (2019–2025)Andrei Seluanov · University of Rochester Medical Center4 papers (2019–2025)Stephen L. Helfand · Brown University3 papers (2019–2021)Jef D. Boeke · NYU Langone Health3 papers (2019–2025)Nicola Neretti · Brown University2 papers (2019–2019)Matthew Simon · University of Rochester2 papers (2019–2019)Marco De Cecco · Brown University2 papers (2019–2019)Fred H. Gage · Salk Institute for Biological Studies2 papers (2021–2025)Anna P. Petrashen · Brown University2 papers (2019–2021)Greta Brocculi · Brown University1 papers (2019–2019)Jayakrishna Ambati · University of Kentucky1 papers (2019–2019)Anjalika Chongtham · Allen Institute for Brain Science1 papers (2025–2025)Raul S. González · Emory University1 papers (2019–2019)Jackson Taylor · Brown University1 papers (2021–2021)Wilson McKerrow · NYU Langone Health1 papers (2021–2021)Oanh Lê · University of Nevada, Las Vegas1 papers (2019–2019)Matthew A. Romero · University of California, Los Angeles1 papers (2022–2022)Steven W. Criscione · Brown University1 papers (2019–2019)Sara B. Linker · Pfizer (United States)1 papers (2021–2021)Taketo Taguchi · University of Rochester1 papers (2019–2019)