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Tim Hon Man Chan

Precigen (United States) · US
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Area of research
Molecular Biology · Oncology
Research interest
Research interests include RNA regulation and disease, CAR-T cell therapy research, RNA Research and Splicing, and Immunotherapy and Immune Responses.
h-index
38
citations
4,765
works
159
NIH funding
primary concept
email

Recent publications

HNRNPM controls circRNA biogenesis and splicing fidelity to sustain cancer cell fitness
eLife 2021cited by 62position: middledoi
RNA editing mediates the functional switch of COPA in a novel mechanism of hepatocarcinogenesis
Journal of Hepatology 2020cited by 73position: middledoi
Suppression of adenosine-to-inosine (A-to-I) RNA editome by death associated protein 3 (DAP3) promotes cancer progression
Science Advances 2020cited by 59position: middledoi
Probabilistic cell-type assignment of single-cell RNA-seq for tumor microenvironment profiling
Nature Methods 2019cited by 422position: middledoi
New High-Throughput Screening Identifies Compounds That Reduce Viability Specifically in Liver Cancer Cells That Express High Levels of SALL4 by Inhibiting Oxidative Phosphorylation
Gastroenterology 2019cited by 64position: middledoi
Bidirectional regulation of adenosine-to-inosine (A-to-I) RNA editing by DEAH box helicase 9 (DHX9) in cancer
Nucleic Acids Research 2018cited by 87position: middledoi
Targeting cancer addiction for SALL4 by shifting its transcriptome with a pharmacologic peptide
Proceedings of the National Academy of Sciences 2018cited by 72position: middledoi
An RNA editing/dsRNA binding-independent gene regulatory mechanism of ADARs and its clinical implication in cancer
Nucleic Acids Research 2017cited by 85position: middledoi
ADAR-Mediated RNA Editing Predicts Progression and Prognosis of Gastric Cancer
Gastroenterology 2016cited by 204position: firstdoi
Recoding RNA editing of AZIN1 predisposes to hepatocellular carcinoma
Nature Medicine 2013cited by 540position: middledoi
A disrupted RNA editing balance mediated by ADARs (Adenosine DeAminases that act on RNA) in human hepatocellular carcinoma
Gut 2013cited by 240position: firstdoi
Adenosine-to-Inosine RNA Editing Mediated by ADARs in Esophageal Squamous Cell Carcinoma
Cancer Research 2013cited by 200position: middledoi
Macrophage migration inhibitory factor induces epithelial to mesenchymal transition, enhances tumor aggressiveness and predicts clinical outcome in resected pancreatic ductal adenocarcinoma
International Journal of Cancer 2012cited by 138position: middledoi
SPOCK1 Is Regulated by CHD1L and Blocks Apoptosis and Promotes HCC Cell Invasiveness and Metastasis in Mice
Gastroenterology 2012cited by 111position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Leilei Chen · National University of Singapore8 papers (2012–2020)Yangyang Song · National University of Singapore7 papers (2013–2020)Henry Yang · National University of Singapore6 papers (2016–2020)Vanessa Hui En Ng · National University of Singapore6 papers (2013–2020)Daniel G. Tenen · Harvard University6 papers (2013–2018)Lihua Qi · National University of Singapore5 papers (2013–2018)Jaymie Siqi Lin · National University of Singapore5 papers (2016–2020)HuiQi Hong · National University of Singapore5 papers (2016–2020)Daryl Jin Tai Tay · National University of Singapore4 papers (2017–2020)Sze Jing Tang · National University of Singapore4 papers (2017–2020)Ömer An · National University Cancer Institute, Singapore3 papers (2018–2020)Ming Liu · Yangtze University3 papers (2012–2013)Jian Han · National University of Singapore3 papers (2018–2020) · 3 papers (2013–2017)Fernando Bellido Molías · National University of Singapore3 papers (2018–2020)Xin‐Yuan Guan · Chongqing Jiaotong University3 papers (2012–2013)Yan Li · University of Chicago2 papers (2013–2013)Jing Fei · First Affiliated Hospital of Shihezi University Medical College2 papers (2013–2013)Kar Tong Tan · National University of Singapore2 papers (2016–2017)Priyankaa Pitcheshwar · National University of Singapore2 papers (2020–2020)
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