Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include RNA modifications and cancer, RNA regulation and disease, Cancer-related molecular mechanisms research, and RNA and protein synthesis mechanisms.
Hepatocyte-macrophage crosstalk via the PGRN-EGFR axis modulates ADAR1-mediated immunity in the liver
ADARs act as potent regulators of circular transcriptome in cancer
Pan-cancer pervasive upregulation of 3′ UTR splicing drives tumourigenesis
Robust generation of human-chambered cardiac organoids from pluripotent stem cells for improved modelling of cardiovascular diseases
HNRNPM controls circRNA biogenesis and splicing fidelity to sustain cancer cell fitness
Cis- and trans-regulations of pre-mRNA splicing by RNA editing enzymes influence cancer development
RNA editing mediates the functional switch of COPA in a novel mechanism of hepatocarcinogenesis
Suppression of adenosine-to-inosine (A-to-I) RNA editome by death associated protein 3 (DAP3) promotes cancer progression
Master transcription factors form interconnected circuitry and orchestrate transcriptional networks in oesophageal adenocarcinoma
The enhancer RNA ARIEL activates the oncogenic transcriptional program in T-cell acute lymphoblastic leukemia
Identification of a novel enhancer of CEBPE essential for granulocytic differentiation
Super-Enhancer-Driven Long Non-Coding RNA LINC01503, Regulated by TP63, Is Over-Expressed and Oncogenic in Squamous Cell Carcinoma
Aberrant hyperediting of the myeloma transcriptome by ADAR1 confers oncogenicity and is a marker of poor prognosis
MethMotif: an integrative cell specific database of transcription factor binding motifs coupled with DNA methylation profiles
Bidirectional regulation of adenosine-to-inosine (A-to-I) RNA editing by DEAH box helicase 9 (DHX9) in cancer
Mitochondrial uncoupling reveals a novel therapeutic opportunity for p53-defective cancers
NCG 5.0: updates of a manually curated repository of cancer genes and associated properties from cancer mutational screenings
NCG 4.0: the network of cancer genes in the era of massive mutational screenings of cancer genomes