Area of research
Biological Psychiatry · Behavioral Neuroscience
Research interest
Research interests include Tryptophan and brain disorders, Stress Responses and Cortisol, Neuroinflammation and Neurodegeneration Mechanisms, and Cancer survivorship and care.
Designing Clinical Trials for an Inflammatory Subtype of Major Depressive Disorder
A randomized proof-of-mechanism trial of TNF antagonism for motivational deficits and related corticostriatal circuitry in depressed patients with high inflammation
Clinical response to EPA supplementation in patients with major depressive disorder is associated with higher plasma concentrations of pro-resolving lipid mediators
Inflammation-Related Functional and Structural Dysconnectivity as a Pathway to Psychopathology
The role of the immune system in posttraumatic stress disorder
Functional connectivity in reward circuitry and symptoms of anhedonia as therapeutic targets in depression with high inflammation: evidence from a dopamine challenge study
Inflammation as a Pathophysiologic Pathway to Anhedonia: Mechanisms and Therapeutic Implications
Omega-3 Fatty Acids for Major Depressive Disorder With High Inflammation
Inflammation, amygdala-ventromedial prefrontal functional connectivity and symptoms of anxiety and PTSD in African American women recruited from an inner-city hospital: Preliminary results
Aiding and Abetting Anhedonia: Impact of Inflammation on the Brain and Pharmacological Implications
Influences of dopaminergic system dysfunction on late-life depression
Epigenetic age acceleration, fatigue, and inflammation in patients undergoing radiation therapy for head and neck cancer: A longitudinal study
Transcriptomic signatures of psychomotor slowing in peripheral blood of depressed patients: evidence for immunometabolic reprogramming
Kynurenines increase MRS metabolites in basal ganglia and decrease resting-state connectivity in frontostriatal reward circuitry in depression
Associations among peripheral and central kynurenine pathway metabolites and inflammation in depression
Gene signatures in peripheral blood immune cells related to insulin resistance and low tyrosine metabolism define a sub-type of depression with high CRP and anhedonia
Inflammation, reward circuitry and symptoms of anhedonia and PTSD in trauma-exposed women
Dose- and time-dependent increase in circulating anti-inflammatory and pro-resolving lipid mediators following eicosapentaenoic acid supplementation in patients with major depressive disorder and chronic inflammation
Identifying Immunophenotypes of Inflammation in Depression: Dismantling the Monolith
Protein and gene markers of metabolic dysfunction and inflammation together associate with functional connectivity in reward and motor circuits in depression
Inflammatory markers are associated with psychomotor slowing in patients with schizophrenia compared to healthy controls
Inflammation and decreased functional connectivity in a widely-distributed network in depression: Centralized effects in the ventral medial prefrontal cortex
Reward-related brain activity and behavior are associated with peripheral ghrelin levels in obesity
What does plasma CRP tell us about peripheral and central inflammation in depression?
Antidepressant treatment resistance is associated with increased inflammatory markers in patients with major depressive disorder
Inflammation negatively correlates with amygdala-ventromedial prefrontal functional connectivity in association with anxiety in patients with depression: Preliminary results
Increased inflammation and brain glutamate define a subtype of depression with decreased regional homogeneity, impaired network integrity, and anhedonia
Role of Inflammation in Depression and Treatment Implications
Glucose and lipid-related biomarkers and the antidepressant response to infliximab in patients with treatment-resistant depression
Imaging the Role of Inflammation in Mood and Anxiety-related Disorders