Area of research
Molecular Biology · Immunology
Research interest
Research focused on HDAC6 and Melanoma, with related work in Antigenicity, Histone, Sting. Notable publications include 'Selective Histone Deacetylase 6 Inhibitors Bearing Substituted Urea Linkers Inhibit Melanoma Cell Growth', 'Epigenetic reprogramming of tumor cell–intrinsic STING function sculpts antigenicity and T cell recognition of melanoma', and 'Essential role of HDAC6 in the regulation of PD‐L1 in melanoma'.
Epigenetic state determines the in vivo efficacy of STING agonist therapy
Epigenetic reprogramming of tumor cell–intrinsic STING function sculpts antigenicity and T cell recognition of melanoma
STING Signaling in Melanoma Cells Shapes Antigenicity and Can Promote Antitumor T-cell Activity
Essential role of HDAC6 in the regulation of PD‐L1 in melanoma
Divergent roles of histone deacetylase 6 (HDAC6) and histone deacetylase 11 (HDAC11) on the transcriptional regulation of IL10 in antigen presenting cells
A Novel Role for Histone Deacetylase 6 in the Regulation of the Tolerogenic STAT3/IL-10 Pathway in APCs
Selective Histone Deacetylase 6 Inhibitors Bearing Substituted Urea Linkers Inhibit Melanoma Cell Growth